IL7R Protein (Fc Tag)
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- Target See all IL7R Proteins
- IL7R (Interleukin 7 Receptor (IL7R))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This IL7R protein is labelled with Fc Tag.
- Purpose
- Recombinant Mouse IL7RA/CD127 Protein (Fc Tag)(Active)
- Sequence
- Glu21-Asp239
- Characteristics
- Recombinant Mouse Interleukin-7 receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Glu21-Asp239 is expressed with a Fc tag at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-7-His(Cat: PKSH032654) at 10μg/ml(100 μl/well) can bind Mouse IL-7RA-Fc.
- Top Product
- Discover our top product IL7R Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- IL7R (Interleukin 7 Receptor (IL7R))
- Alternative Name
- IL7RA/CD127 (IL7R Products)
- Synonyms
- IL7R Protein, CD127 Protein, IL-7Ralpha Protein, CDW127 Protein, IL-7R-alpha Protein, IL7RA Protein, ILRA Protein, IL-7RA Protein, interleukin 7 receptor Protein, IL7R Protein, Il7r Protein
- Background
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Background: Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses.
Synonym: Interleukin-7 receptor subunit alpha, Il7r, IL-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, CD127,IL-7Ralpha
- Molecular Weight
- 52.1 kDa
- NCBI Accession
- NP_032398
- Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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