INHBC Protein (AA 237-352) (His tag)

Catalog No. ABIN6387244

Product Details

Target: INHBC (Inhibin, beta C (INHBC))

Protein Type: Recombinant

Protein Characteristics: AA 237-352

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This INHBC protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSGIDCQGG SRMCCRQEFF VDFREIGWHD WIIQPEGYAM NFCIGQCPLH IAGMPGIAAS FHTAVLNLLK ANTAAGTTGG GSCCVPTARR PLSLLYYDRD SNIVKTDIPD MVVEACGCS

Purity: > 85 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: INHBC (Inhibin, beta C (INHBC))

Alternative Name: INHBC (INHBC Products)

Synonyms: IHBC Protein, inhibin beta C subunit Protein, inhibin beta-C Protein, INHBC Protein, Inhbc Protein

Background: INHBC is the beta C chain of inhibin, a member of the TGF-beta superfamily. This subunit forms heterodimers with beta A and beta B subunits. Inhibins and activins, also members of the TGF-beta superfamily, are hormones with opposing actions and are involved in hypothalamic, pituitary, and gonadal hormone secretion, as well as growth and differentiation of various cell types. Recombinant human INHBC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 14.9 kDa (139aa), confirmed by MALDI-TOF

NCBI Accession: NP_005529

UniProt: P55103

Pathways: Peptide Hormone Metabolism, Hormone Activity