CSTB Protein (AA 1-98) (His tag)

Catalog No. ABIN666707

Product Details

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Protein Type: Recombinant

Protein Characteristics: AA 1-98

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CSTB protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: CSTB, 1-98 aa, Human, His-tagged, Recombinant, E.coli

Purity: > 95 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid in 20mM Tris pH 8.0, 50mM NaCl

Storage: 4 °C

Target Details

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Alternative Name: CSTB (CSTB Products)

Synonyms: CST6 Protein, EPM1 Protein, EPM1A Protein, PME Protein, STFB Protein, ULD Protein, CSTB Protein, Cyb Protein, Epm1 Protein, Stfb Protein, MGC189005 Protein, pme Protein, cst6 Protein, epm1 Protein, stfb Protein, AA960480 Protein, ARABIDOPSIS THALIANA PHYTOCYSTATIN 6 Protein, ATCYS6 Protein, ATCYSB Protein, cystatin B Protein, LOC100008600 Protein, LOC100136235 Protein, CPI1 Protein, cystatin B Protein, cystatin B (stefin B) Protein, cystatin 14a, tandem duplicate 2 Protein, cystatin-B Protein, CSTB Protein, Cstb Protein, cstb Protein, cst14a.2 Protein, CYSB Protein, cpi1 Protein, LOC101123265 Protein

Background: CSTB, also known as Cystatin B is an anti-protease implicated in myoclonus epilepsy, a degenerative disease of the central nervous system. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. This protein is able to form a dimer stabilized by noncovalent forces and is thought to play a role in protecting against the proteases leaking from lysosomes. In cells, CSTB is located in the lysosomes and the cytoplasm, but also in the nucleus. Recombinant CSTB, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Cystatin B, CSTB, Stefin B, PME, CST6, CystatinB CHROW21, CPI B, CYTB, EPM1, Liver thiol proteinase inhibitor, STFB. NCBI no.: NP_000091

Molecular Weight: 13kDa (118aa), confirmed by MALDI-TOF.

Pathways: Response to Water Deprivation