TSTA3 Protein (AA 1-321) (His tag)
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- Target See all TSTA3 Proteins
- TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-321
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TSTA3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- TSTA3, 1-321aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product TSTA3 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 50mM NaCl
- Storage
- 4 °C
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- Target
- TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))
- Alternative Name
- TSTA3 (TSTA3 Products)
- Synonyms
- FX Protein, P35B Protein, SDR4E1 Protein, AI256181 Protein, Tstap35b Protein, p35b Protein, sdr4e1 Protein, TSTA3 Protein, zgc:101805 Protein, si:dkey-235d18none Protein, Fx Protein, tissue specific transplantation antigen P35B Protein, tissue specific transplantation antigen P35B L homeolog Protein, TSTA3 Protein, Tsta3 Protein, tsta3 Protein, tsta3.L Protein
- Background
- TSTA3 is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. Recombinant human TSTA3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: FX, P35B, SDR4E1, GDP-L-fucose synthase. NCBI no.: NP_003304
- Molecular Weight
- 38.0 kDa (341aa) confirmed by MALDI-TOF
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