SEPSECS Protein (AA 1-501) (His tag)

Catalog No. ABIN667283

Product Details

Target: SEPSECS (Sep (O-phosphoserine) tRNA:Sec (Selenocysteine) tRNA Synthase (SEPSECS))

Protein Type: Recombinant

Protein Characteristics: AA 1-501

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SEPSECS protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: SEPSECS, 1-501aa, Human, His tag, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT, 100mM NaCl

Storage: 4 °C

Target Details

Target: SEPSECS (Sep (O-phosphoserine) tRNA:Sec (Selenocysteine) tRNA Synthase (SEPSECS))

Alternative Name: SEPSECS (SEPSECS Products)

Synonyms: LP Protein, PCH2D Protein, SLA Protein, SLA/LP Protein, 9130208G10 Protein, AA986712 Protein, D5Ertd135e Protein, SecS Protein, sla/lpl Protein, zgc:55980 Protein, sepsecs Protein, Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase Protein, Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase L homeolog Protein, SEPSECS Protein, Sepsecs Protein, sepsecs Protein, sepsecs.L Protein

Target Type: Antibody

Background: SEPSECS, also known as SLA/LP autoantigen, catalyzes the final step of sec synthesis by converting O-phosphoseryl-tRNA(sec) to selenocysteinyl-tRNA(sec) using selenophosphate as the selenium donor. Also, this protein is considered a specific marker of autoimmune hepatitis. Recombinant human SEPSECS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: O-phosphoseryl-tRNA(Sec) selenium transferase, O-phosphoseryl-tRNA(Sec) selenium transferase. NCBI no.: NP_058651

Molecular Weight: 57.9kDa (521aa), confirmed by MALDI-TOF

Pathways: SARS-CoV-2 Protein Interactome