C8G Protein (AA 21-202) (His tag)

Catalog No. ABIN667575

Product Details

Target: C8G (Complement Component 8, gamma Polypeptide (C8G))

Protein Type: Recombinant

Protein Characteristics: AA 21-202

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This C8G protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: C8G, 21-202 aa , Human, His tag, E.coli

Purity: > 95 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.15M NaCl.

Storage: 4 °C

Target Details

Target: C8G (Complement Component 8, gamma Polypeptide (C8G))

Alternative Name: C8G (C8G Products)

Synonyms: C8C Protein, complement C8 gamma chain Protein, complement component 8, gamma polypeptide Protein, C8G Protein, C8g Protein

Background: C8gamma, also known as C8G, is one of three polypeptides (along with C8 alpha and C8 beta) that constitutes C8, a component of the complement system. C8 participates in the formation of Membrane Attack Complex (MAC). Patients with deficiency in C8 are vulnerable to certain bacteria infection. C8gamma is a secreted protein that is able to bind retinol and belongs to the lipocalin family and calycin superfamily. It is synthesised in the liver, monocytes and fibroblast and functions to clear pathogens from an infected host. Recombinant human C8G protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: complement component 8, gamma polypeptide, C8C. NCBI no.: AAI13625

Molecular Weight: 22.6 kDa (203aa), confirmed by MALDI-TOF

Pathways: Complement System