PTPMT1 Protein (AA 28-201) (His tag)
-
- Target See all PTPMT1 Proteins
- PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-201
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PTPMT1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- PTPMT1, 28-201 aa , Human, His tag E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product PTPMT1 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.15M NaCl.
- Storage
- 4 °C
-
- Target
- PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))
- Alternative Name
- PTPMT1 (PTPMT1 Products)
- Synonyms
- im:7137979 Protein, zgc:158719 Protein, DUSP23 Protein, MOSP Protein, PLIP Protein, 1110001D10Rik Protein, 2810004N20Rik Protein, Plip Protein, protein tyrosine phosphatase, mitochondrial 1 Protein, PTPMT1 Protein, ptpmt1 Protein, Ptpmt1 Protein
- Background
- PTPMT1 (protein tyrosine phosphatase mitochondrial 1), also known as MOSP or PLIP (phosphoinositide lipid phosphatase) and previously known as DUSP23, is a widely expressed PTP membrane protein with high expression levels in pancreatic beta cells. This protein exclusively localizes to the matrix face of the inner membrane of the mitochondrion. It is responsible for dephosphorylating mitochondrial proteins and therefore plays a significant role in the production of ATP and secretion of insulin. For its substrate, PTPMT1 displays a specific preference for the lipid signaling molecule phosphatidylinositol 5-phosphate. Recombinant human PTPMT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Protein tyrosine phosphatase, mitochondrial 1, DUSP23, FLJ46081, MOSP, PLIP, PNAS-129. NCBI no.: NP_783859
- Molecular Weight
- 22.6 kDa (199aa), confirmed by MALDI-TOF
- Pathways
- Inositol Metabolic Process
-