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CCR8 Protein (Fc Tag)

CCR8 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN6964400
  • Target See all CCR8 Proteins
    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
    Protein Type
    Recombinant
    Origin
    • 8
    • 2
    • 2
    Human
    Source
    • 7
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CCR8 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human CCR8 with C-terminal human Fc tag
    Specificity
    CCR8 (Met1-Lys35) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purification
    affinity purification
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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    Discover our top product CCR8 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Preservative
    Without preservative
    Storage
    -20 °C,-80 °C
    Expiry Date
    12 months
  • Target
    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
    Alternative Name
    CCR8 (CCR8 Products)
    Synonyms
    CC-CKR-8 Protein, CCR-8 Protein, CDw198 Protein, CKRL1 Protein, CMKBR8 Protein, CMKBRL2 Protein, CY6 Protein, GPRCY6 Protein, TER1 Protein, C-C Protein, C-C CKR-8 Protein, CKR-8 Protein, Cmkbr8 Protein, mCCR8 Protein, C-C motif chemokine receptor 8 Protein, chemokine (C-C motif) receptor 8 Protein, CCR8 Protein, Ccr8 Protein
    Background
    Synonymes: CC-CKR-8, CCR-8, CDw198, CKRL1, CMKBR8, CMKBRL2, CY6, GPRCY6, TER1
    Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]
    Molecular Weight
    predicted molecular mass of 30.1 kDa after removal of the signal peptide.The apparent molecular mass of CCR8-hFc is 35-55 kDa due to glycosylation.
    UniProt
    P51685
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