PVRL4 Protein (AA 32-349) (His tag,FITC)
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- Target See all PVRL4 Proteins
- PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 32-349
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PVRL4 protein is labelled with His tag,FITC.
- Characteristics
- FITC-Labeled Human Nectin-4 Protein, His Tag
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product PVRL4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
- Alternative Name
- Nectin-4 (PVRL4 Products)
- Synonyms
- PVRL4 Protein, si:ch211-155e24.1 Protein, 1200017F15Rik Protein, Prr4 Protein, RGD1559826 Protein, EDSS1 Protein, LNIR Protein, PRR4 Protein, nectin-4 Protein, nectin cell adhesion molecule 4 Protein, NECTIN4 Protein, nectin4 Protein, Nectin4 Protein
- Background
- Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50 % , 49 % and 86 %o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.
- Molecular Weight
- 36.0 kDa
- NCBI Accession
- NP_112178
- Pathways
- Cell-Cell Junction Organization
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