RNF43 Protein (AA 44-197) (Fc Tag)
-
- Target See all RNF43 Proteins
- RNF43 (Ring Finger Protein 43 (RNF43))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 44-197
- Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RNF43 protein is labelled with Fc Tag.
- Characteristics
- Human RNF43 Protein, Fc Tag (MALS verified)
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
-
- Target
- RNF43 (Ring Finger Protein 43 (RNF43))
- Alternative Name
- RNF43 (RNF43 Products)
- Synonyms
- RNF124 Protein, URCC Protein, 4732452J19Rik Protein, RGD1305204 Protein, ring finger protein 43 Protein, RNF43 Protein, Rnf43 Protein
- Background
- E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification (By similarity)
- Molecular Weight
- 43.5 kDa
- Pathways
- WNT Signaling
-