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SARS-CoV-2 Spike S1 Protein (P.1 - gamma) (His tag)

Origin: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Gamma Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Catalog No. ABIN6992361
  • Target See all SARS-CoV-2 Spike S1 Proteins
    SARS-CoV-2 Spike S1
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    P.1 - gamma
    Origin
    • 95
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Gamma
    Source
    • 87
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SARS-CoV-2 Spike S1 protein is labelled with His tag.
    Purpose
    SARS-CoV-2 S1 protein (L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y), His Tag
    Sequence
    AA 16-685
    Characteristics
    SARS-CoV-2 S1 protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1). L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y mutations were identified in the SARS-CoV-2 variant (known as P.1 lineage) which emerged in Brazil.
    Purity
    >90 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product SARS-CoV-2 Spike S1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
  • Target
    SARS-CoV-2 Spike S1
    Alternative Name
    SARS-CoV-2 S1 protein (SARS-CoV-2 Spike S1 Products)
    Synonyms
    E2 Protein, Surface Glycoprotein Protein, S Protein
    Target Type
    Viral Protein
    Background
    It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
    Molecular Weight
    76.9 kDa
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