YAP1 Protein (His tag)

Catalog No. ABIN7092709

Product Details

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This YAP1 protein is labelled with His tag.

Purpose: Recombinant human YAP1 protein with C-terminal 6xHis tag

Specificity: YAP1 (Met1-Leu504) 6xHis tag

Characteristics: Extracellular Domain Protein

Purification: affinity purification

Purity: The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Alternative Name: YAP1 (YAP1 Products)

Synonyms: YAP Protein, YAP2 Protein, YAP65 Protein, YKI Protein, xyap Protein, yap Protein, yap2 Protein, yap65 Protein, yki Protein, AI325207 Protein, Yap Protein, Yap65 Protein, Yki Protein, Yorkie Protein, cb194 Protein, sb:cb194 Protein, si:ch211-181p1.5 Protein, si:dkey-3b8.3 Protein, wu:fc18c04 Protein, zgc:158380 Protein, Yes associated protein 1 Protein, Yes associated protein 1 S homeolog Protein, yes-associated protein 1 Protein, Yes-associated protein 1 Protein, YAP1 Protein, yap1.S Protein, Yap1 Protein, yap1 Protein

Background: Synonymes: COB1, YAP, YAP2, YAP65, YKI
Description: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: predicted molecular mass of 55.3 kDa after removal of the signal peptide.

Gene ID: 10413

UniProt: P46937

Pathways: MAPK Signaling, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha