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Epiregulin Protein (EREG) (Fc Tag)

EREG Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7092773
  • Target See all Epiregulin (EREG) Proteins
    Epiregulin (EREG)
    Protein Type
    Recombinant
    Origin
    • 11
    • 4
    • 1
    Human
    Source
    • 7
    • 4
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This Epiregulin protein is labelled with Fc Tag.
    Purpose
    Recombinant Human EREG with C-terminal human Fc tag
    Specificity
    EREG (Val63-Leu108) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purification
    affinity purification
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product EREG Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    Epiregulin (EREG)
    Alternative Name
    EREG (EREG Products)
    Synonyms
    EREG Protein, ER Protein, EPR Protein, proepiregulin Protein, epiregulin Protein, EREG Protein, ereg Protein, Ereg Protein
    Background
    Synonymes: Ep
    Description: This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues. [provided by RefSeq, Jul 2015]
    Molecular Weight
    predicted molecular mass of 31.4 kDa after removal of the signal peptide. The apparent molecular mass of EREG-hFc is 35-55 kDa due to glycosylation.
    UniProt
    O14944
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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