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FOLR2 Protein (His tag)

FOLR2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7092810
  • Target See all FOLR2 Proteins
    FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
    Protein Type
    Recombinant
    Origin
    • 8
    • 2
    • 2
    Human
    Source
    • 8
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This FOLR2 protein is labelled with His tag.
    Purpose
    Recombinant human FOLR2 protein with C-terminal 6xHis tag
    Specificity
    FOLR2 (Thr17-His228) 6xHis tag
    Characteristics
    Extracellular Domain Protein
    Purification
    affinity purification
    Purity
    The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product FOLR2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
    Alternative Name
    FOLR2 (FOLR2 Products)
    Synonyms
    FOLR2 Protein, BETA-HFR Protein, FBP Protein, FBP/PL-1 Protein, FR-BETA Protein, FR-P3 Protein, FBP2 Protein, Folbp-2 Protein, Folbp2 Protein, folate receptor 1 Protein, folate receptor beta Protein, folate receptor 2 (fetal) Protein, FOLR1 Protein, FOLR2 Protein, Folr2 Protein
    Background
    Synonymes: BETA-HFR
    Description: The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
    Molecular Weight
    predicted molecular mass of 25.4 kDa after removal of the signal peptide. The apparent molecular mass of FOLR2-His is 25-35 kDa due to glycosylation.
    UniProt
    P14207
    Pathways
    Dicarboxylic Acid Transport
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