PUMA Protein (His tag)
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- Target See all PUMA (BBC3) Proteins
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PUMA protein is labelled with His tag.
- Purpose
- Recombinant Human PUMA/BBC3 protein (His Tag)
- Sequence
- 1M-193N
- Characteristics
- A DNA sequence encoding the Human PUMA/BBC3 (Q9BXH1-1) (1M-193N) was expressed with a polyhistidine tag at the N-terminus.
- Purity
- >90 % as determined by reducing SDS-PAGE.
- Biological Activity Comment
- Immunogen(E-AB-40332)
- Top Product
- Discover our top product BBC3 Protein
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BCL2 Binding Component 3 (BBC3) (AA 141-261) protein (His-IF2DI Tag)
BBC3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
BCL2 Binding Component 3 (BBC3) (AA 1-193) protein (Strep Tag)Crystallography grade BBC3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
BCL2 Binding Component 3 (BBC3) (AA 1-261) protein (Strep Tag)Crystallography grade BBC3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
BCL2 Binding Component 3 (BBC3) (AA 1-193) protein (Strep Tag)Crystallography grade BBC3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
BCL2 Binding Component 3 (BBC3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)BBC3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
BCL2 Binding Component 3 (BBC3) (AA 76-170) protein (His tag,Strep II tag)BBC3 Origin: Human Host: Escherichia coli (E. coli) Recombinant ~95 % WB, ELISA, MS
BCL2 Binding Component 3 (BBC3) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)BBC3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as sterile Tris,EDTA,PH 8.0.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Samples are stable for up to twelve months from date of receipt at -70°C.Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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- Target
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
- Alternative Name
- PUMA/BBC3 (BBC3 Products)
- Synonyms
- BBC3 Protein, Puma Protein, JFY-1 Protein, JFY1 Protein, PUMA Protein, PUMA/JFY1 Protein, BCL2 binding component 3 Protein, Bcl-2 binding component 3 Protein, BBC3 Protein, Bbc3 Protein, bbc3 Protein
- Background
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Background: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis . Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
Synonym: BBC 3, Bbc3, BBC3_HUMAN, BCL 2 binding component 3, Bcl-2-binding component 3, BCL2 binding component 3, JFY 1, JFY-1, JFY1, p53 up regulated modulator of apoptosis, p53 up-regulated modulator of apoptosis, p53 Upregulated Modulator of Apoptosis, PUMA alpha, PUMA/JFY1
- Molecular Weight
- 20.1kDa
- Pathways
- p53 Signaling, Positive Regulation of Endopeptidase Activity
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