BAX Protein (His tag)
-
- Target See all BAX Proteins
- BAX (BCL2-Associated X Protein (BAX))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BAX protein is labelled with His tag.
- Purpose
- Recombinant Human BAX/BCL2L4 Protein (His Tag)
- Sequence
- Met 1-Gln171
- Characteristics
- Recombinant Human BCL2-associated X protein is produced by our E.coli expression system and the target gene encoding Met1-Gln171 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product BAX Protein
-
BCL2-Associated X Protein (BAX) (AA 1-192) protein (GST tag)
BAX Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
BCL2-Associated X Protein (BAX) (AA 1-100) protein (GST tag)BAX Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
BCL2-Associated X Protein (BAX) (AA 1-110) protein (His-IF2DI Tag)BAX Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
BCL2-Associated X Protein (BAX) (AA 1-171) protein (His tag)BAX Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
BCL2-Associated X Protein (BAX) (AA 1-192) protein (Strep Tag)Crystallography grade BAX Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
BCL2-Associated X Protein (BAX) (AA 1-192) protein (Strep Tag)Crystallography grade BAX Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
-
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,2 mM EDTA,5 % Threhalose,30 % Glycerol, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Target
- BAX (BCL2-Associated X Protein (BAX))
- Alternative Name
- BAX/BCL2L4 (BAX Products)
- Synonyms
- BAX-ALPHA Protein, bax-A Protein, xBax Protein, xlbax Protein, BAX Protein, bax Protein, fj16e01 Protein, wu:fc50b10 Protein, wu:fj16e01 Protein, BCL2L4 Protein, zgc:112983 Protein, BCL2 associated X, apoptosis regulator Protein, BCL2-associated X protein L homeolog Protein, BCL2-associated X protein Protein, bcl2-associated X protein, a Protein, bcl2-associated X protein, b Protein, BAX Protein, bax.L Protein, bax Protein, baxa Protein, Bax Protein, baxb Protein
- Background
-
Background: Apoptosis Regulator BAX (BAX) belongs to the Bcl-2 family. BAX exists as a homodimer and is expressed in a wide variety of tissues. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa). Although both isoforms contain BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. BAX accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. BAX also promotes activation of CASP3, and thereby apoptosis.
Synonym: Apoptosis Regulator BAX, Bcl-2-Like Protein 4, Bcl2-L-4, BAX, BCL2L4
- Molecular Weight
- 22.1 kDa
- UniProt
- Q07812
- Pathways
- p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
-
