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CD74 Protein (His tag)

CD74 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >90 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7320931
  • Target See all CD74 Proteins
    CD74 (HLA-DR-gamma (CD74))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 13
    • 10
    • 3
    Mouse
    Source
    • 9
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CD74 protein is labelled with His tag.
    Purpose
    Recombinant Mouse CD74 protein (His Tag)
    Sequence
    56Q-279L
    Characteristics
    A DNA sequence encoding theMouse CD74 protein (P04441) (56Q-279L) was expressed with a polyhistidine tag at the N-terminus.
    Purity
    >90 % as determined by reducing SDS-PAGE.
    Biological Activity Comment
    Immunogen(E-AB-40348)
    Top Product
    Discover our top product CD74 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD74 (HLA-DR-gamma (CD74))
    Alternative Name
    CD74 (CD74 Products)
    Synonyms
    DHLAG Protein, HLADG Protein, II Protein, Ia-GAMMA Protein, CLIP Protein, Ii Protein, INVG34 Protein, Iclp-1 Protein, iclp1 Protein, wu:fb11f09 Protein, wu:fb12a01 Protein, wu:fb13d06 Protein, wu:fk94e07 Protein, Iclp-2 Protein, cd74 Protein, iclp2 Protein, zgc:123161 Protein, CD74 molecule Protein, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) Protein, CD74 molecule, major histocompatibility complex, class II invariant chain a Protein, CD74 molecule, major histocompatibility complex, class II invariant chain b Protein, CD74 Protein, Cd74 Protein, cd74a Protein, cd74b Protein
    Background

    Background: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.

    Synonym: CD 74,CD74,CD74 antigen (invariant polypeptide of major histocompatibility complex,class II antigen-associated),CD74 antigen,CD74 Molecule,CD74 Molecule,major histocompatibility complex,class II invariant chain,CLIP,DHLAG,Gamma chain of class II antigens,HG2A,HLA class II histocompatibility antigen gamma chain,HLA DR antigens associated invariant chain,HLA DR gamma,HLA-DR antigens-associated invariant chain,HLA-DR-gamma,HLADG,HLADR antigens associated invariant chain,Ia antigen associated invariant chain,Ia antigen-associated invariant chain,Ia associated invariant chain,Ia gamma,Ii,Invariant polypeptide of major histocompatibility complex class II antigen associated,la-gamma,Major histocompatibility complex class II invariant chain,MHC HLA DR gamma chain,MHC HLA-DR gamma chain,p33,p35,Protein 41

    Molecular Weight
    25.3kDa
    UniProt
    P04441
    Pathways
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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