LAIR2 Protein (His tag)
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- Target See all LAIR2 Proteins
- LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LAIR2 protein is labelled with His tag.
- Purpose
- Active Recombinant Human LAIR-2/CD306 Protein
- Sequence
- QEGALPRPSI SAEPGTVISP GSHVTFMCRG PVGVQTFRLE REDRAKYKDS YNVFRLGPSE SEARFHIDSV SEGNAGLYRC LYYKPPGWSE HSDFLELLVK ESSGGPDSPD TEPGSSAGTV PGTEASGFDA P
- Specificity
- Gln22-Pro152
- Purity
- > 90 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 0.1 EU/μg of the protein by LAL method.
- Biological Activity Comment
- Measured by the ability of the immobilized protein to support the adhesion of HT-29 human colon adenocarcinoma cells. When 5 x 104 cells/well are added to rhLAIR-2 coated plates (50 μg/mL with 100 μL/well), approximately 50%-60% will adhere after 10 minutes at 37°C.
- Top Product
- Discover our top product LAIR2 Protein
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Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) (AA 22-152) protein (His-Avi Tag)
LAIR2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) (AA 22-152) protein (His-Avi Tag,Biotin)LAIR2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) protein (Fc Tag)LAIR2 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) (AA 1-152) protein (GST tag)LAIR2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) (AA 22-152) protein (His tag)Crystallography grade LAIR2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) (AA 22-152) protein (His tag,AVI tag,Biotin)LAIR2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Target
- LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
- Alternative Name
- LAIR-2/CD306 (LAIR2 Products)
- Synonyms
- CD306 Protein, leukocyte associated immunoglobulin like receptor 2 Protein, LAIR2 Protein
- Background
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Description: Leukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD36, is a 131 amino acid protein containing one lg-like C2-type domain, making it a member of the Ig superfamily. When compared to LAIR-1, its transmembrane counterpart, it shares 83 % aa identity across the signal sequence and extracellular domains, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similar adhesion profiles. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. LAIR2 is thought to be secreted and may help modulate mucosal tolerance.
Name: LAIR2,CD306
- Gene ID
- 3904
- UniProt
- Q6ISS4
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