LY96 Protein (Fc Tag)
-
- Target See all LY96 Proteins
- LY96 (Lymphocyte Antigen 96 (LY96))
- Protein Type
- Recombinant
-
Origin
- Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LY96 protein is labelled with Fc Tag.
- Purpose
- Recombinant Mouse LY-96/ESOP-1 Protein (Fc Tag)
- Sequence
- Met1-Asn160
- Characteristics
- A DNA sequence encoding the mouse LY96 (Q9JHF9) (Met1-Asn160) was expressed with the Fc region of human IgG1 at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product LY96 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- LY96 (Lymphocyte Antigen 96 (LY96))
- Alternative Name
- LY-96/ESOP-1 (LY96 Products)
- Synonyms
- MD2 Protein, ESOP-1 Protein, MD-2 Protein, ly-96 Protein, Ly-96 Protein, Md2 Protein, lymphocyte antigen 96 Protein, LY96 Protein, Ly96 Protein
- Background
-
Background: LY-96, also known as ESOP-1, is a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS). LY-96 also cooperates with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. It enhances TLR4-dependent activation of NF-kappa-B. ESOP-1 has 160 amino acids, the sequence of which shows 64 % identity with human ESOP-1/MD-2. ESOP-1 mRNA is highly expressed in the mouse embryos at 7.5 days after coitus.
Synonym: ESOP-1,MD-2,MD2
- Molecular Weight
- 43.4 kDa
- UniProt
- Q9JHF9
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
-