NCR3 Protein (Fc Tag)
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- Target See all NCR3 Proteins
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NCR3 protein is labelled with Fc Tag.
- Purpose
- Human NKp30 / NCR3 / CD337 Protein, Llama IgG2b Fc Tag, low endotoxin
- Sequence
- Leu 19 - Gly 135
- Characteristics
- Human NKp30, Llama IgG2b Fc Tag (NC3-H5256) is expressed from human 293 cells (HEK293). It contains AA Leu 19 - Gly 135 (Accession # NP_667341.1).
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 0.01 EU per μg by the LAL method.
- Top Product
- Discover our top product NCR3 Protein
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Natural Cytotoxicity Triggering Receptor 3 (NCR3) protein (His-Avi Tag)
NCR3 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-138) protein (Fc Tag)NCR3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-138) protein (His-Avi Tag,Biotin)NCR3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-135) protein (His-DYKDDDDK-Strep II Tag)NCR3 Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 1-201) protein (GST tag)NCR3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-135) protein (Fc Tag)NCR3 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- Application Notes
- This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 40.7 kDa. The protein migrates as 50-55 kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
- Alternative Name
- NKp30 / NCR3 / CD337 (NCR3 Products)
- Synonyms
- MGC133750 Protein, 1C7 Protein, CD337 Protein, LY117 Protein, MALS Protein, NKp30 Protein, Nkp30 Protein, natural cytotoxicity triggering receptor 3 Protein, NCR3 Protein, Ncr3 Protein
- Background
- Synonyms:NCR3,CD337,NKp30,1C7,LY117,MALS,Description:Natural cytotoxicity triggering receptor 3 (NCR3) is also known as Activating natural killer receptor p30, Natural killer cell p30-related protein (NK-p30), CD antigen CD337, 1C7, LY117. NCR3 /CD337 /NKp30 belongs to the natural cytotoxicity receptor (NCR) family. NCR3 /NKp30 contains one Ig-like (immunoglobulin-like) domain. NCR3 /NKp30 is selectively expressed by all resting and activated NK cells and weakly expressed in spleen. NCR3 is homodimer in the unliganted form. NCR3 interacts with CD3Z. NCR3 interacts with and is activated by binding to NCR3LG1 or BAG6. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.
- Molecular Weight
- 40.7 kDa
- NCBI Accession
- NP_667341
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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