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DLL3 Protein (AA 27-215) (His-DYKDDDDK Tag)

DLL3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274484
  • Target See all DLL3 Proteins
    DLL3 (delta Like Protein 3 (DLL3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 27-215
    Origin
    • 14
    • 4
    • 2
    • 2
    • 1
    Human
    Source
    • 19
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This DLL3 protein is labelled with His-DYKDDDDK Tag.
    Purpose
    Human DLL3 (27-215) Protein
    Sequence
    Ala27-Glu215
    Characteristics
    Recombinant Human DLL3 (27-215) Protein is expressed from HEK293 with His tag and Flag tag at the N-Terminus.It contains Ala27-Glu215.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human DLL3 (27-215) , His Tag at 0.2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product DLL3 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in PBS, 360 mM NaCl, 200 mM L-arginine ( pH 8.0).
    Storage
    -80 °C
    Storage Comment
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    DLL3 (delta Like Protein 3 (DLL3))
    Alternative Name
    DLL3 (DLL3 Products)
    Synonyms
    SCDO1 Protein, pu Protein, pudgy Protein, delta like canonical Notch ligand 3 Protein, delta-like 3 (Drosophila) Protein, DLL3 Protein, Dll3 Protein
    Background
    Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).
    Molecular Weight
    22.30 kDa. Due to glycosylation, the protein migrates to 24-25 kDa based on Tris-Bis PAGE result.
    Pathways
    Notch Signaling
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