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EPH Receptor A3 Protein (EPHA3) (AA 1-514) (His tag)

EPHA3 Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274552
  • Target See all EPH Receptor A3 (EPHA3) Proteins
    EPH Receptor A3 (EPHA3)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-514
    Origin
    • 17
    • 7
    • 3
    Dog
    Source
    • 12
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This EPH Receptor A3 protein is labelled with His tag.
    Purpose
    Canine EPHA3 Protein
    Sequence
    Met1-His514
    Characteristics
    Recombinant Canine EPHA3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Met1-His514.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    EPH Receptor A3 (EPHA3)
    Alternative Name
    EPHA3 (EPHA3 Products)
    Synonyms
    EK4 Protein, ETK Protein, ETK1 Protein, HEK Protein, HEK4 Protein, TYRO4 Protein, EPHA3 Protein, AW492086 Protein, Cek4 Protein, End3 Protein, Hek Protein, Hek4 Protein, Mek4 Protein, Tyro4 Protein, CEK4 Protein, EPH receptor A3 Protein, ephrin type-A receptor 3 Protein, Eph receptor A3 Protein, EPHA3 Protein, LOC100439679 Protein, Epha3 Protein
    Background
    Erythropoietin-producing hepatocellular carcinoma cell surface type-A receptor 3 (EPHA3) has been found to promote the proliferation and survival of prostate cancer (PCa) cell lines and prostate tumor development in nude mice. The interaction of AR and SP1 contributes to regulate EPHA3 expression, and the SP1 binding sites (-295~-261) in the EPHA3 core promoter region is crucial to the regulation of EPHA3 expression in response to androgen hormone stimuli.
    Molecular Weight
    58.97 kDa. Due to glycosylation, the protein migrates to 60-65 kDa based on Tris-Bis PAGE result.
    UniProt
    F1P925
    Pathways
    RTK Signaling, Regulation of Cell Size
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