SIRPB1 Protein (AA 30-371, Isoform 3) (His-Avi Tag,Biotin)
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- Target See all SIRPB1 Proteins
- SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-371, Isoform 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SIRPB1 protein is labelled with His-Avi Tag,Biotin.
- Purpose
- Biotinylated Human SIRP Beta 1 Isoform 3 Protein
- Sequence
- Glu30-Leu371
- Characteristics
- Recombinant Biotinylated Human SIRP Beta 1 Isoform 3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu30-Leu371.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product SIRPB1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))
- Alternative Name
- SIRP Beta 1 (SIRPB1 Products)
- Synonyms
- CD172b Protein, SIRP-BETA-1 Protein, SIRPB1 Protein, SIRPG Protein, signal regulatory protein beta 1 Protein, signal-regulatory protein beta-1 Protein, signal-regulatory protein beta-1 isoform 3 Protein, SIRPB1 Protein, LOC458036 Protein, LOC458430 Protein, LOC485809 Protein, LOC715912 Protein, LOC100458151 Protein
- Background
- Signal regulatory protein β1 (SIRPB1) is a signal regulatory protein member of the immunoglobulin superfamily and is capable of modulating receptor tyrosine kinase-coupled signaling. Copy number variations at the SIRPB1 locus were previously reported to associate with prostate cancer aggressiveness in patients.SIRPB1 gene amplification and overexpression were detected in prostate cancer specimens. The knockdown of SIRPB1 significantly suppressed cell growth in colony formation assays and cell mobility.
- Molecular Weight
- 39.9 kDa. Due to glycosylation, the protein migrates to 55-68 kDa based on Tris-Bis PAGE result.
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