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CD51/CD61 Protein (His tag)

MALS verified ITGAV/ITGB3 Origin: Rat Host: HEK-293 Cells Recombinant 95,00 %
Catalog No. ABIN7447982
  • Target See all CD51/CD61 (ITGAV/ITGB3) Proteins
    CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
    Protein Type
    Recombinant
    Origin
    • 4
    • 3
    • 1
    Rat
    Source
    • 8
    HEK-293 Cells
    Purification tag / Conjugate
    This CD51/CD61 protein is labelled with His tag.
    Purpose
    Rat Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free (MALS verified)
    Sequence
    Phe 31 - Pro 988 (ITGAM) & Ser 27 - Asp 717 (ITGB3)
    Characteristics
    Rat ITGAV&ITGB3 Heterodimer, His Tag&Tag Free is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Pro 988 (ITGAM) & Ser 27 - Asp 717 (ITGB3) (Accession # NP_001385621.1 (ITGAM) & Q8R2H2 (ITGB3).
    Purity
    95,00 %
    Endotoxin Level
    1.0 EU per μg
    Grade
    MALS verified
    Top Product
    Discover our top product ITGAV/ITGB3 Protein
  • Comment

    Rat ITGAV&ITGB3 Heterodimer, His Tag&Tag Free, has a calculated MW of 112.3 kDa (ITGAV) & 81.6 kDa (ITGB3). Subunit ITGAV is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB3 contains no tag but a basic tail at the C-terminus.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM Tris,150 mM NaCl, pH 7.5
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
    Alternative Name
    Integrin alpha V beta 3 (ITGAV/ITGB3 Products)
    Synonyms
    CD51 Protein, MSK8 Protein, VNRA Protein, VTNR Protein, integrin subunit alpha V Protein, ITGAV Protein
    Background
    Synonyms:Integrin alpha V beta 3,ITGAV&ITGB3,Description:Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Also, Integrin alpha-V/beta-3 acts as a receptor for herpes virus 8/HHV-8, coxsackievirus A9, Hantaan virus, cytomegalovirus/HHV-5, human metapneumovirus, human parechovirus 1 and west nile virus. Furthermore, in case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
    Molecular Weight
    112.3 kDa | 81.6 kDa
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