CD51/CD61 Protein (AA 31-988) (Fc Tag)
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- Target See all CD51/CD61 (ITGAV/ITGB3) Proteins
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 31-988
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD51/CD61 protein is labelled with Fc Tag.
- Purpose
- Mouse Integrin alpha V beta 3 (ITGAV & ITGB3) Heterodimer Protein
- Sequence
- Phe31-Val988 (ITGAV) acidic tail & Glu26-Asp717 (ITGB3) basic tail
- Specificity
- Uni-Prot: P43406 (ITGAV), , O54890 (ITGB3)
- Characteristics
- Recombinant Mouse Integrin alpha V beta 3 (ITGAV & ITGB3) Heterodimer Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe31-Val988(ITGAV) acidic tail & Glu26-Asp717(ITGB3) basic tail.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product ITGAV/ITGB3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
- Alternative Name
- Integrin alpha V beta 3 (ITGAV & ITGB3) Heterodimer (ITGAV/ITGB3 Products)
- Synonyms
- CD51 Protein, MSK8 Protein, VNRA Protein, VTNR Protein, integrin subunit alpha V Protein, ITGAV Protein
- Background
- ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.
- Molecular Weight
- 131.48 kDa(ITGAV)&101.58 kDa(ITGB3). Due to enzyme lysis and glycosylation, the protein migrates to 110-135 kDa and 50-60 kDa based on Tris-Bis PAGE result.
- UniProt
- P43406
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