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CD43 Protein (AA 20-248) (Fc Tag)

SPN Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7504271
  • Target See all CD43 (SPN) Proteins
    CD43 (SPN) (Sialophorin (SPN))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 20-248
    Origin
    • 11
    • 5
    • 1
    • 1
    Mouse
    Source
    • 6
    • 5
    • 4
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD43 protein is labelled with Fc Tag.
    Purpose
    Mouse CD43 Protein
    Sequence
    Asp20-Gly248
    Characteristics
    Recombinant Mouse CD43 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Asp20-Gly248.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
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    Discover our top product SPN Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CD43 (SPN) (Sialophorin (SPN))
    Alternative Name
    CD43 (SPN Products)
    Synonyms
    CD43 Protein, GALGP Protein, GPL115 Protein, LSN Protein, A630014B01Rik Protein, Cd43 Protein, Galgp Protein, Ly-48 Protein, Ly48 Protein, Lsn Protein, Lsn1 Protein, gpL115 Protein, sialophorin Protein, SPN Protein, Spn Protein
    Background
    CD43 is a large transmembrane protein involved in T cell activation. Previous studies of CD43-/- mice in viral models have demonstrated a role for CD43 in Th1/Th2 skewing, activation of Foxp3 Treg, and T cell apoptosis. CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage. CD43 is directly involved in the contact between cells participating in a series of events such as signaling, adherence and host parasite interactions.
    Molecular Weight
    49.30 kDa. Due to glycosylation, the protein migrates to 75-120 kDa based on Tris-Bis PAGE result.
    UniProt
    P15702
    Pathways
    Regulation of Leukocyte Mediated Immunity
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