DLL4 Protein (AA 27-524) (His tag)
-
- Target See all DLL4 Proteins
- DLL4 (delta-Like 4 (DLL4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-524
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DLL4 protein is labelled with His tag.
- Purpose
- Human DLL4 Protein
- Sequence
- Ser27-Pro524
- Characteristics
- Recombinant Human DLL4 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ser27-Pro524.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product DLL4 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Supplied as 0.22 μm filtered solution in PBS, 200 mM L-Arginine ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- DLL4 (delta-Like 4 (DLL4))
- Alternative Name
- DLL4 (DLL4 Products)
- Synonyms
- hdelta2 Protein, Delta4 Protein, si:ch211-244p18.5 Protein, zgc:136596 Protein, delta like canonical Notch ligand 4 Protein, delta-like 4 (Drosophila) Protein, DLL4 Protein, Dll4 Protein, dll4 Protein
- Background
- Delta-like protein 4 (DLL4) is a type I membrane protein belonging to the Delta/Serrate/Lag2 (DSL) family of Notch ligands. Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate.
- Molecular Weight
- 55.38 kDa. Due to glycosylation, the protein migrates to 56-70 kDa based on Tris-Bis PAGE result.
- Pathways
- Notch Signaling
-