E-cadherin Protein (AA 155-709) (His tag)

Catalog No. ABIN7504313

Product Details

Target: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Protein Type: Recombinant

Protein Characteristics: AA 155-709

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This E-cadherin protein is labelled with His tag.

Purpose: Human E-Cadherin/Cadherin-1 Protein

Sequence: Asp155-Ala709

Characteristics: Recombinant Human E-Cadherin/Cadherin-1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Asp155-Ala709.

Purity: > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCL ( pH 8.0). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Alternative Name: E-Cadherin (CDH1 Products)

Synonyms: Arc-1 Protein, CD324 Protein, CDHE Protein, ECAD Protein, LCAM Protein, UVO Protein, E-cadherin Protein, cdh1 Protein, si:dz180o5.2 Protein, uvo Protein, lcam Protein, E-Cad Protein, XBcad Protein, l-cam Protein, xcdh1 Protein, cdhc-A Protein, xb-cad Protein, XTCAD-1 Protein, c-cadherin Protein, cadherin-1 Protein, uvomorulin Protein, XB-cadherin Protein, arc-1 Protein, cd324 Protein, cdhe Protein, ecad Protein, AA960649 Protein, E-cad Protein, Ecad Protein, L-CAM Protein, Um Protein, cadherin 1 Protein, si:busm1-180o5.2 Protein, cadherin 1, type 1, E-cadherin (epithelial) Protein, cadherin 1, type 1 S homeolog Protein, CDH1 Protein, si:busm1-180o5.2 Protein, cdh1 Protein, Cdh1 Protein, cdh1.S Protein

Background: E-cadherin is the core component of epithelial adherens junctions, essential for tissue development, differentiation, and maintenance. It is also fundamental for tissue barrier formation, a critical function of epithelial tissues.

Molecular Weight: 61.62 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.

Pathways: WNT Signaling, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation