MAPKAP Kinase 5 Protein (AA 1-471) (Strep II tag)

Catalog No. ABIN7504513

Product Details

Target: MAPKAP Kinase 5 (MAPKAPK5) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))

Protein Type: Recombinant

Protein Characteristics: AA 1-471

Origin: Human

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This MAPKAP Kinase 5 protein is labelled with Strep II tag.

Purpose: Human PRAK Protein

Sequence: Met1-Gln471

Characteristics: Recombinant Human PRAK Protein is expressed from Baculovirus-Insect Cells with Strep-II tag at the C-terminus.It contains Met1-Gln471.

Purity: > 90 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl, 2 mM CaCl₂ ( pH 8.0).

Storage: -80 °C

Storage Comment: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: MAPKAP Kinase 5 (MAPKAPK5) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))

Alternative Name: PRAK (MAPKAPK5 Products)

Synonyms: MAPKAPK5 Protein, MK5 Protein, PRAK Protein, MAPKAP-K5 Protein, MK-5 Protein, mitogen-activated protein kinase-activated protein kinase 5 Protein, MAP kinase-activated protein kinase 5 Protein, MAPKAPK5 Protein, mapkapk5 Protein, Mapkapk5 Protein

Background: The p38 mitogen-activated protein kinase (MAPK) pathway plays an important role in cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated protein kinase (PRAK, also known as mitogen-activated protein kinase activated protein kinase 5 [MAPKAPK5]) functions downstream of p38alpha and p38beta in mediating the signaling of the p38 pathway.

Molecular Weight: 55.57 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result.

NCBI Accession: NP_003659

Pathways: MAPK Signaling