VNN1 Protein (AA 24-488) (His tag)
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- Target See all VNN1 Proteins
- VNN1 (Vanin 1 (VNN1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-488
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This VNN1 protein is labelled with His tag.
- Purpose
- Mouse VNN1 Protein
- Sequence
- Leu24-Asn488
- Characteristics
- Recombinant Mouse VNN1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu24-Asn488.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Vanin 1 (VNN1) (AA 22-491) protein (His tag)Crystallography grade VNN1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4. Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- VNN1 (Vanin 1 (VNN1))
- Alternative Name
- VNN1 (VNN1 Products)
- Synonyms
- HDLCQ8 Protein, Tiff66 Protein, V-1 Protein, hdlcq8 Protein, tiff66 Protein, vnn1.1 Protein, vanin-1 Protein, vanin 1 Protein, pantetheinase Protein, VNN1 Protein, Vnn1 Protein, vnn1 Protein, LOC100217969 Protein
- Background
- Vanin-1 (VNN1) is anchored to the cellular membrane with pantetheinase activity, which hydrolyzes pantetheine to produce cysteamine. VNN1 can promote oxidative stress and the inflammatory response. Additionally, VNN1 has been confirmed to be overexpressed in cancer tissues of patients with PCAD and can be used as a blood biomarker for the discrimination of PCAD from type 2 diabetes.
- Molecular Weight
- 53.14 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9Z0K8
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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