IFNA1 Protein (His tag)

Catalog No. ABIN7536323

Product Details

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This IFNA1 protein is labelled with His tag.

Purpose: Recombinant Mouse IFNA1 Protein

Sequence: CDLPQTHNLR NKRALTLLVQ MRRLSPLSCL KDRKDFGFPQ EKVDAQQIKK AQAIPVLSEL TQQILNIFTS KDSSAAWNTT LLDSFCNDLH QQLNDLQGCL MQQVGVQEFP LTQEDALLAV RKYFHRITVY LREKKHSPCA WEVVRAEVWR ALSSSANVLG RLREEK

Specificity: Cys24-Lys189

Purity: > 97 % by SDS-PAGE.

Sterility: 0.22 μm filtered

Endotoxin Level: < 0.1EU/μg

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Concentration: 1.65 mg/mL

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Target Details

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Alternative Name: IFNA1 (IFNA1 Products)

Synonyms: IFL Protein, IFN Protein, IFN-ALPHA Protein, IFN-alphaD Protein, IFNA13 Protein, IFNA@ Protein, Ifa1 Protein, IFN-ALPHA-1 Protein, IFN1@ Protein, IFNA1 Protein, IFN-alpha Protein, IFN-gamma Protein, IFNA Protein, IFNA2 Protein, IFNA6 Protein, IFN-alpha1 Protein, interferon alpha 13 Protein, interferon alpha 1 Protein, interferon, alpha 1 Protein, interferon, alpha 13 Protein, interferon Protein, interferon-alpha 1 Protein, interferon, alpha, leukocyte Protein, interferon-alpha-14 Protein, IFNA13 Protein, IFNA1 Protein, Ifna1 Protein, ifna1 Protein, IFNA3 Protein, IFN-ALPHA-14 Protein

Background:

Description: IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs can activate immune cells, such as natural killer cells and macrophages, they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes, and they also increase the ability of uninfected host cells to resist new infection by the virus. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes. IFNA1 is produced by macrophages and has antiviral activities.

Name: Ifa1, If1ai14,IFNA1

Gene ID: 15962

UniProt: P01572

Pathways: JAK-STAT Signaling, Hepatitis C