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Prostate Specific Antigen Protein (PSA) (His tag)

PSA Origin: Human Host: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. Active
Catalog No. ABIN7535810
  • Target See all Prostate Specific Antigen (PSA) Proteins
    Prostate Specific Antigen (PSA)
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 11
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Prostate Specific Antigen protein is labelled with His tag.
    Purpose
    Active Recombinant Human PSA/KLK3 Protein
    Sequence
    APLILSRIVG GWECEKHSQP WQVLVASRGR AVCGGVLVHP QWVLTAAHCI RNKSVILLGR HSLFHPEDTG QVFQVSHSFP HPLYDMSLLK NRFLRPGDDS SHDLMLLRLS EPAELTDAVK VMDLPTQEPA LGTTCYASGW GSIEPEEFLT PKKLQCVDLH VISNDVCAQV HPQKVTKFML CAGRWTGGKS TCSGDSGGPL VCNGVLQGIT SWGSEPCALP ERPSLYTKVV HYRKWIKDTI VANP
    Specificity
    Ala18-Pro261
    Purity
    > 95 % by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    <0.1EU/μg
    Biological Activity Comment
    Measured by its ability to cleave the colorimetric peptide substrate, Succinyl-Arg-Pro-Tyr-p- Nitroanilide (Suc-RPY-pNA). The specific activity is >160 pmol/min/μg, as measured under the described conditions.
    Top Product
    Discover our top product PSA Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Target
    Prostate Specific Antigen (PSA)
    Alternative Name
    PSA/KLK3 (PSA Products)
    Synonyms
    APS Protein, KLK2A1 Protein, PSA Protein, hK3 Protein, KLK3 Protein, Klk1c10l2 Protein, RSGK-50 Protein, RSKG-50 Protein, rGK-3 Protein, Kal-3 Protein, Kal3 Protein, Klk3 Protein, AAP-S Protein, MP100 Protein, Psa Protein, R74825 Protein, goku Protein, kallikrein related peptidase 3 Protein, kallikrein 3 Protein, kallikrein 1-related peptidase C3 Protein, kallikrein B, plasma 1 Protein, aminopeptidase puromycin sensitive Protein, KLK3 Protein, Klk1c3 Protein, Klkb1 Protein, Npepps Protein
    Background

    Description: KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that is synthesized in the epithelial cells of the prostate gland and is present in seminal plasma. KLK3, also known as Prostate Specific Antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases. KLK3 contains one peptidase S1 domain. KLK3 is a glycoprotein produced almost exclusively by the prostate gland. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.

    Name: APS, KLK2A1, PSA, hK3,KLK3, APS, prostate-specific antigen,KLK2A1,PSA,hK3

    Gene ID
    354
    UniProt
    P07288
    Pathways
    Complement System
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