RBP4 Protein (Fc Tag,His tag)

Catalog No. ABIN7534463

Product Details

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This RBP4 protein is labelled with Fc Tag,His tag.

Purpose: Active Recombinant Human Retinol-binding protein 4/PRBP Protein

Sequence: ERDCRVSSFR VKENFDKARF SGTWYAMAKK DPEGLFLQDN IVAEFSVDET GQMSATAKGR VRLLNNWDVC ADMVGTFTDT EDPAKFKMKY WGVASFLQKG NDDHWIVDTD YDTYAVQYSC RLLNLDGTCA DSYSFVFSRD PNGLPPEAQK IVRQRQEELC LARQYRLIVH NGYCDGRSER NLL

Specificity: Glu19-Leu201

Purity: > 97 % by SDS-PAGE.

Sterility: 0.22 μm filtered

Endotoxin Level: < 0.1 EU/μg of the protein by LAL method.

Biological Activity Comment: Measured by its binding ability in a functional ELISA. Immobilized Human RBP4 Protein at 2 μg/mL (100 μL/well) can bind RBP4 Rabbit mAb with a linear range of 0.12-2.1 ng/mL.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Target Details

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Alternative Name: Retinol-binding protein 4/PRBP (RBP4 Products)

Synonyms: RDCCAS Protein, RBP Protein, RNBP Protein, rbp4 Protein, MGC54038 Protein, srbp Protein, PRBP Protein, RBPA Protein, Rbp-4 Protein, fb23c12 Protein, rbp Protein, wu:fb23c12 Protein, wu:fb58d04 Protein, wu:fb72b04 Protein, zgc:86911 Protein, retinol binding protein 4 Protein, renin binding protein Protein, retinol binding protein 4 S homeolog Protein, retinol binding protein 4 A, plasma Protein, retinol binding protein 4, plasma Protein, retinol binding protein 4 L homeolog Protein, RBP4 Protein, RENBP Protein, rbp4.S Protein, rbp4 Protein, Rbp4 Protein, RBP4A Protein, rbp4.L Protein

Background:

Description: This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.

Name: MCOPCB10, RDCCAS,RBP4,RDCCAS

Gene ID: 5950

UniProt: P02753

Pathways: Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response