VEGFC Protein (His tag)
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- Target See all VEGFC Proteins
- VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
- Protein Type
- Recombinant
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Origin
- Rat, Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This VEGFC protein is labelled with His tag.
- Purpose
- Recombinant Mouse/Rat VEGF-C Protein
- Sequence
- AHYNTEILKS IDNEWRKTQC MPREVCIDVG KEFGAATNTF FKPPCVSVYR CGGCCNSEGL QCMNTSTGYL SKTLFEITVP LSQGPKPVTI SFANHTSCRC MSKLDVYRQV HSIIRR
- Specificity
- Ala108-Arg223
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- <1EU/μg
- Top Product
- Discover our top product VEGFC Protein
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Vascular Endothelial Growth Factor C (VEGFC) (AA 103-227) protein (His-Avi Tag)
VEGFC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Vascular Endothelial Growth Factor C (VEGFC) (AA 103-227) protein (His-Avi Tag,Biotin)VEGFC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Vascular Endothelial Growth Factor C (VEGFC) (AA 1-419) protein (GST tag)VEGFC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Vascular Endothelial Growth Factor C (VEGFC) (AA 103-227) protein (His tag)VEGFC Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Vascular Endothelial Growth Factor C (VEGFC) (AA 112-227) protein (GST tag)VEGFC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Vascular Endothelial Growth Factor C (VEGFC) (AA 112-227) protein (His tag)Crystallography grade VEGFC Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Vascular Endothelial Growth Factor C (VEGFC) (AA 112-227), (full length) protein (GST tag)VEGFC Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Concentration
- 0.58 mg/mL
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, 10 % glycerol, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
- Alternative Name
- VEGF-C (VEGFC Products)
- Synonyms
- VEGFC Protein, vegf-c Protein, xvegf-c Protein, Flt4-L Protein, VRP Protein, AW228853 Protein, VEGF-C Protein, vascular endothelial growth factor c Protein, vascular endothelial growth factor C Protein, vascular endothelial growth factor C S homeolog Protein, vegfc Protein, VEGFC Protein, vegfc.S Protein, Vegfc Protein
- Background
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Description: Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotein, as a ligand for two receptors, VEGFR-3 (Flt4), and VEGFR-2. VEGF-C may function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis. VEGF-C protein is over-expressed in various human cancers including breast cancer and prostate cancer. VEGF-C/VEGFR-3 axis, through different signaling pathways, plays a critical role in cancer progression by regulating different cellular functions, such as invasion, proliferation, and resistance to chemotherapy. Thus, targeting the VEGF-C/VEGFR-3 axis may be therapeutically significant for certain types of tumors.
Name: VEGFC,Flt4-L,LMPH1D,VRP
- Gene ID
- 22341
- UniProt
- P97953
- Pathways
- RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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