FGF1 Protein

Catalog No. ABIN935136

This Recombinant FGF1 protein is expressed in Escherichia coli (E. coli).

Quick Overview for FGF1 Protein (ABIN935136)

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % pure

Product Details

Characteristics: Purified recombinant Human Acidic Fibroblast Growth Factor
Expression System: E.coli
Bioactivity: < 3 ng/mL for half maximum stimulation of cell proliferation with bovine aortic endothelial cells (BAE cells)

Purification: Affinity chromatography

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied in lyophilized form in 1 mL phosphate buffered saline (pH 6), supplemented with 5 mM glutathion.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C in lyophilized form. Following reconstitution aliquot and store at -20 °C for long term storage.

Target Details

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Alternative Name: FGF1

Background: This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described.
Alternative Names: FGF 1, ACGFB protein, Prostatropin, Acidic Fibroblast Growth Factor, ECGF protein, FGF-1, HBGF-1 protein, FGFA protein, FGF 1 protein, ECGFA protein, FGF1, FGF-1 protein, Heparin-binding growth factor 1, AFGF protein

Molecular Weight: 20 kDa

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway