Epigen Protein
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- Target See all Epigen (EPGN) Proteins
- Epigen (EPGN) (Epithelial Mitogen (EPGN))
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- AVTVTPPITA QQADNIEGPI ALKFSHLCLE DHNSYCINGA CAFHHELEKA ICRCFTGYTG ERCEHLTLTS Y
- Characteristics
- Determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells. The expected ED50 for this effect is 150-300 ng/ml,corresponding to a specific activity of > 3.3×103 units/mg.
- Purity
- > 98 % by SDS-PAGE and HPLC analyses.
- Endotoxin Level
- Level Less than 1EU/µg of rHuEPG as determined by LAL method
- Top Product
- Discover our top product EPGN Protein
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Epithelial Mitogen (EPGN) (AA 24-95) protein (His tag)
EPGN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Epithelial Mitogen (EPGN) (AA 1-133) protein (GST tag)EPGN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Epithelial Mitogen (EPGN) (AA 23-110) protein (His tag)EPGN Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
Epithelial Mitogen (EPGN) protein (Myc-DYKDDDDK Tag)EPGN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
- Storage
- 4 °C
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- Target
- Epigen (EPGN) (Epithelial Mitogen (EPGN))
- Alternative Name
- Epigen (EPG) (EPGN Products)
- Synonyms
- ALGV3072 Protein, EPG Protein, PRO9904 Protein, 2310069M11Rik Protein, epigen Protein, RGD1560084 Protein, epithelial mitogen Protein, EPGN Protein, Epgn Protein
- Background
- Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence. Synonym: Epigen (EPG), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.
- Molecular Weight
- Approximately 7.9kDa monomeric protein, containing 72 amino acid residues, which comprises the EGF homologous portion of the Epigen precursor.
- Pathways
- RTK Signaling, EGFR Signaling Pathway
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