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|Antigen||Chemokine (C-C Motif) Receptor 7 (CCR7) Antibodies|
|Epitope||AA 2-22 Alternatives|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This CCR7 antibody is un-conjugated Alternatives|
Immunochromatography (IC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
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Product Details anti-CCR7 AntibodyTarget Details CCR7 Application Details Handling Images
|Cross-Reactivity (Details)||Peptide sequence is <50 % identical to other mouse chemokine receptors inthis region and crossreacts with human CCR7|
|Immunogen||CCR7 antibody was raised in goat using a synthetic peptide DPGKPRKNVLVVALLVIFQVC corresponding to amino acid residues 2-22 of mouse CCR7 as the immunogen.|
|Plasmids, Primers & others|
Target Details CCR7Product Details anti-CCR7 Antibody Application Details Handling Images back to top
|Alternative Name||CCR7 (CCR7 Antibody Abstract)|
|Background||C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. CCR7 has also recently been designated CD197 (cluster of differentiation 197). The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes.|
|Pathways||Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process|
Application DetailsProduct Details anti-CCR7 Antibody Target Details CCR7 Handling Images back to top
ELISA: 1:100,000, FC: 1:10, IC: 1:250, IHC: 1:250, WB: 1:1,000
Optimal conditions should be determined by the investigator.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CCR7 Antibody Target Details CCR7 Application Details Images back to top
|Buffer||10 mM KHPO4, pH 7.2, with 140 M NaCl, 1 mg/mL BSA and 0.1 % NaN3.|
|Precaution of Use||This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage||-20 °C/-80 °C|
|Storage Comment||Aliquot and store at -20 °C for short term storage, -70 °C for long-term storage.|
ImagesProduct Details anti-CCR7 Antibody Target Details CCR7 Application Details Handling back to top