Browse our anti-CD46 Molecule, Complement Regulatory Protein (CD46) Antibodies

Full name:: anti-CD46 Molecule, Complement Regulatory Protein Antibodies (CD46)

On www.antibodies-online.com are 447 CD46 Molecule, Complement Regulatory Protein (CD46) Antibodies from 0 different suppliers available. A total of 517 CD46 Molecule, Complement Regulatory Protein products are currently listed.

Synonyms:: AHUS2, Mcp, MIC10, TLX, TRA2.10

list all antibodies	Gene Name	GeneID	UniProt
Anti-Human CD46	CD46	4179	P15529
Anti-Mouse CD46	CD46	17221	O88174
Anti-Rat CD46	CD46	29333	Q9Z0M4
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Relevant Pathways for anti-CD46 Molecule, Complement Regulatory Protein Antibodies

Regulation of Actin Filament Polymerization

More product categories related to CD46 Molecule, Complement Regulatory Protein Antibody

Top referenced anti-CD46 Molecule, Complement Regulatory Protein Antibodies

Human Monoclonal CD46 Primary Antibody for FACS, IP - ABIN94153 : Oliaro, Pasam, Waterhouse, Browne, Ludford-Menting, Trapani, Russell: Ligation of the cell surface receptor, CD46, alters T cell polarity and response to antigen presentation. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
Show all 14 Pubmed References
Human Monoclonal CD46 Primary Antibody for FACS, IP - ABIN94151 : Liszewski, Kemper, Price, Atkinson: Emerging roles and new functions of CD46. in Springer seminars in immunopathology 2005 (PubMed)
Show all 14 Pubmed References
Human Monoclonal CD46 Primary Antibody for FACS, IP - ABIN94149 : Gaggar, Shayakhmetov, Lieber: CD46 is a cellular receptor for group B adenoviruses. in Nature medicine 2003 (PubMed)
Show all 13 Pubmed References
Human Monoclonal CD46 Primary Antibody for FACS, IP - ABIN125715 : Okada, Liszewski, Atkinson, Caparon: Membrane cofactor protein (CD46) is a keratinocyte receptor for the M protein of the group A streptococcus. in Proceedings of the National Academy of Sciences of the United States of America 1995 (PubMed)
Show all 12 Pubmed References
Human Monoclonal CD46 Primary Antibody for FACS, IP - ABIN94152 : Marie, Astier, Rivailler, Rabourdin-Combe, Wild, Horvat: Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell induced inflammation. in Nature immunology 2002 (PubMed)
Show all 12 Pubmed References
Human Monoclonal CD46 Primary Antibody for FACS, IP - ABIN192263 : Kälin, Amstutz, Gastaldelli, Wolfrum, Boucke, Havenga, DiGennaro, Liska, Hemmi, Greber: Macropinocytotic uptake and infection of human epithelial cells with species B2 adenovirus type 35. in Journal of virology 2010 (PubMed)
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Human Monoclonal CD46 Primary Antibody for FACS, WB - ABIN2191980 : Matsui, Sakurai, Katayama, Kurachi, Tashiro, Sugio, Kawabata, Mizuguchi: Enhanced transduction efficiency of fiber-substituted adenovirus vectors by the incorporation of RGD peptides in two distinct regions of the adenovirus serotype 35 fiber knob. in Virus research 2010 (PubMed)
Show all 6 Pubmed References
Human Polyclonal CD46 Primary Antibody for WB - ABIN1881186 : Riley, Kemper, Leung, Atkinson: Characterization of human membrane cofactor protein (MCP; CD46) on spermatozoa. in Molecular reproduction and development 2002 (PubMed)
Show all 5 Pubmed References
Human Monoclonal CD46 Primary Antibody for FACS, WB - ABIN2191979 : Seya, Hara, Matsumoto, Akedo: Quantitative analysis of membrane cofactor protein (MCP) of complement. High expression of MCP on human leukemia cell lines, which is down-regulated during cell differentiation. in Journal of immunology (Baltimore, Md. : 1950) 1990 (PubMed)
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Rat (Rattus) Monoclonal CD46 Primary Antibody for IA, IF - ABIN2192126 : Mizuno, Harris, Johnson, Morgan: Rat membrane cofactor protein (MCP; CD46) is expressed only in the acrosome of developing and mature spermatozoa and mediates binding to immobilized activated C3. in Biology of reproduction 2004 (PubMed)
Show all 4 Pubmed References

More Antibodies against CD46 Molecule, Complement Regulatory Protein Interaction Partners

Human CD46 Molecule, Complement Regulatory Protein (CD46) interaction partners

these data suggest a possible mechanism underlying the regulatory function of CD46 on T cells.
study demonstratede that MMP-9 (show MMP9 Antibodies)-mediated shedding of CD46 is an integral part of autocrine Th1 (show TH1L Antibodies) regulation and that this pathway is dysregulated in T cells from patients with systemic lupus erythematosus
the cell surface expression level of CD46 was markedly higher in patient myeloma cells with 1q gain than in those with normal 1q copy number.
Our findings reveal a novel role of CD46 in accelerating inflammatory responses upon meningococcal infection or LPS (show IRF6 Antibodies) stimulation by regulating the functional polarization and survival of macrophages.
study reveals common CD46 and IFI44L (show IFI44L Antibodies) SNPs associated with measles-specific humoral immunity, and highlights the importance of alternative splicing/virus cellular receptor isoform usage as a mechanism explaining inter-individual variation in immune response after live measles vaccine
study showed no genotype differences in CD46 IVS1-1724 C>G Single nucleotide polymorphis (SNP) between Recurrent Spontaneous Abortion and fertile women
Isoforms of CD46 impact on HHV-6B infection and thereby in part explain the distinct tropism of HHV-6AGS and HHV-6BPL1.
This study suggests that the promoter polymorphism (rs2796267, -496 A/G) CD46 gene may be related to susceptibility of acute renal allograft rejection in Korean kidney transplantation recipients.
provides insight into CD46 alternative splicing regulation with implications for its function in the immune system and for genetic disease
CD46 controls both Th1 (show TH1L Antibodies) activation and regulation via a miR (show MLXIP Antibodies)-150-dependent mechanism.

Mouse (Murine) CD46 Molecule, Complement Regulatory Protein (CD46) interaction partners

Changes in CD46 expression may lead to changes in VEGF (show VEGFA Antibodies) and play a pathologic role in the development of age-related macular degeneration.
Our findings provide evidence for expression of CD46 in the mouse eye and a role for CD46 in protection against laser-induced choroidal neovascularization
This fusion is mediated by the interaction between viral glycoproteins expressed on the membrane of the infected cells and CD46 on the glial targets, and is also observed using cells expressing recombinant MV glycoproteins.
CD46 isoforms function as receptors for human herpesvirus 6 and measles virus
Disruption of mouse CD46 causes an accelerated spontaneous acrosome reaction in sperm and increased male fertility
CD46 has a role as a receptor for fusion and entry of human herpesvirus 6 into target cells

Pig (Porcine) CD46 Molecule, Complement Regulatory Protein (CD46) interaction partners

The results obtained in this study showed that both porcine CD46 and heparan sulfates play a major role in the initial steps of classical swine fever virus infection.

Cow (Bovine) CD46 Molecule, Complement Regulatory Protein (CD46) interaction partners

Study shows the existence of 10 distinct allelic versions of the CCP1 (show AGTPBP1 Antibodies) module of CD46; ectopic expression of the 10 bovine CD46 isoforms rendered the PK15 cells permissive to bovine viral diarrhea virus.
localization of CD46 on bovine sperm membrane

CD46 Molecule, Complement Regulatory Protein (CD46) Antigen Profile

Antigen Summary

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with CD46 Molecule, Complement Regulatory Protein (CD46)

CD46 molecule (CD46) antibody
CD46 antigen, complement regulatory protein (Cd46) antibody
CD46 molecule (Cd46) antibody
CD46 molecule, complement regulatory protein (CD46) antibody

AHUS2 antibody
Mcp antibody
MIC10 antibody
TLX antibody
TRA2.10 antibody

Protein level used designations for CD46

CD46 antigen, complement regulatory protein , antigen identified by monoclonal antibody TRA-2-10 , complement membrane cofactor protein , measles virus receptor , membrane cofactor protein , membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) , trophoblast leucocyte common antigen , trophoblast leukocyte common antigen , trophoblast-lymphocyte cross-reactive antigen , brain microvascular membrane cofactor , membrane cofactor protein(GMP1-full)

GENE ID	SPECIES
4179	Homo sapiens
17221	Mus musculus
29333	Rattus norvegicus
396922	Sus scrofa
280851	Bos taurus
100135498	Cavia porcellus

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