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|Antigen||Bone Morphogenetic Protein 6 (BMP6) Antibodies|
|Conjugate||This BMP6 antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-BMP6 AntibodyTarget Details BMP6 Application Details Handling Images
|Specificity||This antibody detects endogenous levels of BMP-6 protein. (region surrounding Ala152)|
|Cross-Reactivity (Details)||Species reactivity (tested):Human.|
|Purity||> 95 % by SDS-PAGE|
|Plasmids, Primers & others|
Target Details BMP6Product Details anti-BMP6 Antibody Application Details Handling Images back to top
|Alternative Name||BMP6 (BMP6 Antibody Abstract)|
|Background||Bone morphogenic proteins (BMPs) are members of the TGFbeta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFbeta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.Synonyms: BMP-6, Bone morphogenetic protein 6, VGR, VGR1|
|Molecular Weight||approx. 57 kDa|
|Pathways||Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process|
Application DetailsProduct Details anti-BMP6 Antibody Target Details BMP6 Handling Images back to top
Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-BMP6 Antibody Target Details BMP6 Application Details Images back to top
|Buffer||Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
ImagesProduct Details anti-BMP6 Antibody Target Details BMP6 Application Details Handling back to top