anti-Human POR antibody for Immunohistochemistry

Recommended POR Antibody (supplied by: Log in to see )

Antigen
P450 (Cytochrome) Oxidoreductase (POR) Antibodies
  • CPR
  • CYPOR
  • P450R
  • POR
  • CCR
  • CG11567
  • DMR
  • DmCPR
  • Dmel\\CG11567
  • NCPR
  • P450
  • cpr
  • zgc:110032
  • npr
  • xpor
  • 4933424M13Rik
  • PORCINO
  • T5J17.90
  • T5J17_90
  • TFC C
  • TUBULIN-FOLDING COFACTOR C
  • cytochrome p450 oxidoreductase
  • P450 (cytochrome) oxidoreductase
  • Cytochrome P450 reductase
  • P450 (cytochrome) oxidoreductase a
  • P450 (cytochrome) oxidoreductase L homeolog
  • NADPH--cytochrome P450 reductase
  • C-CAP/cofactor C-like domain-containing protein
  • POR
  • Por
  • Cpr
  • pora
  • por.L
  • LOC100406157
  • por
  • LOC100619047
Epitope
Middle Region
7
7
6
4
4
4
3
2
2
2
2
2
2
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
144
67
65
9
9
9
8
6
5
5
4
4
3
3
2
2
2
2
2
2
2
2
1
1
Host
Rabbit
89
42
18
3
Clonality
Polyclonal
Conjugate
This POR antibody is un-conjugated
5
5
5
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
141
102
57
34
31
30
23
22
6
1
1
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Catalog No. ABIN2773843
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.672457 ABIN2781830 IHC WB Rabbit N-Term Log in to see Polyclonal 0
8.672457 ABIN1867349 ICC IHC WB Rabbit IgG AA 77-518 Log in to see Polyclonal 0
8.672457 ABIN1804636 FACS IF IHC IHC (p) WB Mouse IgG1 Log in to see 6C4 0
8.672457 ABIN3197773 IHC WB Rabbit Log in to see Polyclonal 0
8.672457 ABIN2719045 FACS IHC WB Mouse IgG1 Log in to see 4G2 0
8.672457 ABIN2719048 FACS IF IHC WB Mouse IgG1 Log in to see 1B11 0
8.672457 ABIN2719049 FACS IF IHC WB Mouse IgG2a Log in to see 5B3 0
8.672457 ABIN2719050 IF IHC WB Mouse IgG1 Log in to see 5B6 0
8.672457 ABIN2719043 FACS IF IHC WB Mouse IgG1 Log in to see 3H10 0
8.672457 ABIN2719044 IF IHC WB Mouse IgG1 Log in to see 5H5 0
8.672457 ABIN2719046 FACS IF IHC WB Mouse IgG1 Log in to see 2E4 0
8.672457 ABIN2719051 FACS IF IHC WB Mouse IgG2a Log in to see 3F10 0
8.672457 ABIN5965525 IHC WB Rabbit IgG Log in to see Polyclonal 0
8.672457 ABIN6005958 IHC WB Rabbit IgG full length Log in to see Polyclonal 0
1 ABIN1497746 FACS IF IHC IHC (p) WB Mouse IgG2a Log in to see 5B3 0
1 ABIN1497743 FACS IF IHC IHC (p) WB Mouse IgG1 Log in to see 2E4 0
1 ABIN1497748 IF IHC IHC (p) WB Mouse IgG1 Log in to see 5B6 0
1 ABIN1497744 FACS IF IHC IHC (p) WB Mouse IgG2a Log in to see 3F10 0
1 ABIN1497747 FACS IHC IHC (p) WB Mouse IgG1 Log in to see 4G2 0
1 ABIN1497749 IF IHC IHC (p) WB Mouse IgG1 Log in to see 5H5 0

General

Antigen P450 (Cytochrome) Oxidoreductase (POR) Antibodies
Epitope Middle Region
(7), (7), (6), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
(144), (67), (65), (9), (9), (9), (8), (6), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Host Rabbit
(89), (42), (18), (3)
Clonality
Polyclonal
Conjugate This POR antibody is un-conjugated
(5), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(141), (102), (57), (34), (31), (30), (23), (22), (6), (1), (1)
Pubmed 1 reference available
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Product Details anti-POR Antibody

Target Details POR Application Details Handling References for anti-POR antibody (ABIN2773843) Images
Blocking Peptide Blocking peptide for this product available: ABIN981990
Sequence VVHTDIDAAK VYMGEMGRLK SYENQKPPFD AKNPFLAAVT TNRKLNQGTE
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
Characteristics This is a rabbit polyclonal antibody against POR. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human POR
Plasmids, Primers & others

Target Details POR

Product Details anti-POR Antibody Application Details Handling References for anti-POR antibody (ABIN2773843) Images back to top
Antigen
Alternative Name POR (POR Antibody Abstract)
Background POR is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this POR gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CPR, CYPOR, DKFZp686G04235, FLJ26468, P450R
Protein Interaction Partner: UBC, CYP2C9, PGRMC1, STAT1, INSIG1, CYP3A4, CYP2E1, CYP2D6, CYP2C19, CYP2A6, CYP1A2, UBD, SUMO2, RABEPK, FANCC, CYB5A, CYP17A1, XRCC6, HMOX1,
Protein Size: 680
Molecular Weight 77 kDa
Gene ID 5447
NCBI Accession NM_000941, NP_000932
UniProt Q63HL4
Pathways Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process

Application Details

Product Details anti-POR Antibody Target Details POR Handling References for anti-POR antibody (ABIN2773843) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 680 AA

Restrictions For Research Use only

Handling

Product Details anti-POR Antibody Target Details POR Application Details References for anti-POR antibody (ABIN2773843) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-POR antibody (ABIN2773843)

Product Details anti-POR Antibody Target Details POR Application Details Handling Images back to top
Product cited in:

Lee, Kim, Yoon, Lee: "Cytochrome P450 system expression and DNA adduct formation in the liver of Zacco platypus following waterborne benzo(a)pyrene exposure: implications for biomarker determination." in: Environmental toxicology, Vol. 29, Issue 9, pp. 1032-42, 2014

Images

Product Details anti-POR Antibody Target Details POR Application Details Handling References for anti-POR antibody (ABIN2773843) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-P450 (Cytochrome) Oxidoreductase (POR) (Middle Region) antibody (ABIN2773843) anti-P450 (Cytochrome) Oxidoreductase (POR) (Middle Region) antibody
Western Blotting (WB) image for anti-P450 (Cytochrome) Oxidoreductase (POR) (Middle Region) antibody (ABIN2773843) WB Suggested Anti-POR Antibody Titration: 0.25ug/ml Positive Control: 293T cells l...