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HLAE Antigen Profile
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
Alternative names and synonyms associated with HLAE
major histocompatibility complex, class I, E (HLA-E) ELISA Kit
EA1.2 ELISA Kit
EA2.1 ELISA Kit
HLA-6.2 ELISA Kit
MHC ELISA Kit
QA1 ELISA Kit
Protein level used designations for HLAE
HLA class I histocompatibility antigen, E alpha chain
, HLA class I histocompatibility antigen, alpha chain E
, MHC HLA-E alpha-1
, MHC HLA-E alpha-2.1
, MHC class I antigen E
, lymphocyte antigen