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POLR2E rs3787016T allele was associated with an increased cancer risk in Chinese population
POLR2E rs3787016 C/T and HULC rs7763881 were associated with a significantly decreased risk for ESCC 0.005). ANRIL rs2151280 T/C SNP was not associated with risk of ESCC.
ELL has an early and essential role during rapid high-amplitude gene expression that is required for both Pol II pause site entry and release
crystal of RPB5 diffracted to 2.8 A resolution and belonged to space group P4(3)2(1)2.
RPB5-mediating protein is required for the proliferation of hepatocellular carcinoma cells.
Results pinpoint critical residues for RNA polymerase II subunit 5 binding to RAP30 and/or to HBx, and identify these residues in both mammalian cells and in an in vitro binding assay.
Is part of an RNA polymerase II-associated complex with possible chaperone activity.
This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11.
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
, DNA directed RNA polymerase II polypeptide E
, DNA-directed RNA polymerases I, II, and III subunit RPABC1
, DNA-directed RNA polymerase II subunit E
, RNA polymerases I, II, and III subunit ABC1
, RPB5 homolog
, DNA directed RNA polymerase II 23 kda polypeptide
, DNA-directed RNA polymerase II 23 kDa polypeptide