Coronavirus (2019-nCoV) Research Antibodies, Proteins and Kits

With the outbreak of a new SARS-like coronavirus in the Chinese city of Wuhan, infection prevention and control has become critical. The current pneumonia outbreak is caused by the newly identified coronavirus 2019-nCoV, officially known as severe acute respiratory syndrome coronavirus 2 ().) 1,2 . SARS-CoV-2 is an enveloped, positive-sense, single-stranded member of the Betacoronavirus Genus 3,6 , that also includes (Sequence Similarity: 70%, see hCoV Proteome Microarray (ABIN6936258) ), MERS CoV (Sequence Similarity: 40%) and .

PhoenixDx® SARS-CoV-2 Detection Kit (RT-PCR-based)

Kit for quantitative RT-PCR-based detection of SARS-CoV-2

Detects 3 gene sequences: E gene, N gene and RdRP gene

Minimizes the chance of false-negative results caused by an altered target sequence

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2019-nCoV Proteome Microarray

Utilizes 9,766 peptides to cover the whole proteome of SARS-CoV-2 (GenBank ID: MN908947.3)(4)

The peptides overlap by 13 amino acids and ensure high resolution epitope data.

Detects IgG and IgM antibody responses on epitope level in plasma, serum or purified protein.

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SARS-CoV-2 Antibodies & Proteins used in current Efforts

Product Type Source Cat. No. Delivery Quantity Price Relevance ProductGrid: uniqueid
anti-SARS-CoV-2 Envelope Protein (SARS-CoV-2 E) (N-Term) antibody Primary Rabbit ABIN1031551 2 to 3 Days 0.1 mg $370.00 element-ABIN1031551
anti-SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (C-Term) antibody Primary Rabbit ABIN1030641 2 to 3 Days 0.1 mg $370.00 element-ABIN1030641
Novel Coronavirus (SARS-CoV-2) IgG Antibody Detection Kit (Colloidal Gold Method) Kit ABIN6952310 2 to 3 Days 20 strips $313.50 element-ABIN6952310
Novel Coronavirus (SARS-CoV-2) IgM Antibody Detection Kit (Colloidal Gold Method) Kit ABIN6952311 2 to 3 Days 20 strips $313.50 element-ABIN6952311
SARS-Coronavirus Spike Protein (SARS-CoV S) (C-Term) peptide Peptide ABIN1382273 2 to 3 Days 0.05 mg $115.50 element-ABIN1382273
SARS-CoV-2 Envelope Protein (SARS-CoV-2 E) (N-Term) peptide Peptide ABIN1382276 2 to 3 Days 0.05 mg $115.50 element-ABIN1382276
SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (AA 1-419) protein (His tag) Protein HEK-293 Cells ABIN6952315 2 to 3 Days 200 μL $213.40 element-ABIN6952315
SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (AA 1-419) protein (His tag) Protein Escherichia coli (E. coli) ABIN6952312 2 to 3 Days 100 μg $312.40 element-ABIN6952312
SARS-CoV-2 S1 Subunit Protein (RBD) (SARS-CoV-2 S1 RBD) (AA 319-541) protein (AVI tag,Biotin,His tag) Protein HEK-293 Cells ABIN6952456 2 to 3 Days 200 μg $1,518.00 element-ABIN6952456
SARS-CoV-2 S1 Subunit Protein (RBD) (SARS-CoV-2 S1 RBD) (AA 319-541) protein (Fc Tag) Protein HEK-293 Cells ABIN6952316 2 to 3 Days 200 μL $213.40 element-ABIN6952316
SARS-CoV-2 S1 Subunit Protein (RBD) (SARS-CoV-2 S1 RBD) (AA 319-541) protein (His tag) Protein HEK-293 Cells ABIN6952317 2 to 3 Days 200 μL $213.40 element-ABIN6952317
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 16-1213), (Arg683Ala-Mutant), (Arg685Ala-Mutant) (Active) protein (His tag) Protein HEK-293 Cells ABIN6952523 2 to 3 Days 50 μg $495.00 element-ABIN6952523
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 16-685) protein (AVI tag,Biotin,His tag) Protein HEK-293 Cells ABIN6952457 2 to 3 Days 200 μg $1,518.00 element-ABIN6952457
SARS-CoV-2 Spike Subunit S1 (SARS-CoV-2 S1) (AA 16-690) protein (His tag) Protein HEK-293 Cells ABIN6952318 2 to 3 Days 200 μL $213.40 element-ABIN6952318
SARS-CoV-2 Spike Subunit S1 (SARS-CoV-2 S1) (AA 319-541) protein (His tag) Protein Escherichia coli (E. coli) ABIN6952323 2 to 3 Days 100 μg $312.40 element-ABIN6952323
SARS-CoV-2 Spike Subunit S1 (SARS-CoV-2 S1) (AA 697-1213) protein (His tag) Protein HEK-293 Cells ABIN6952319 2 to 3 Days 200 μL $213.40 element-ABIN6952319
SARS-CoV-2 Spike Subunit S2 (SARS-CoV-2 S2) (AA 697-1213) protein (His tag) Protein Escherichia coli (E. coli) ABIN6952326 2 to 3 Days 100 μg $312.40 element-ABIN6952326

Coronavirus Antibodies & Proteins used in current nCoV Efforts

Product Type Cat. No. Delivery Quantity Price Relevance ProductGrid: uniqueid
Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 2 (ACE2) (AA 1-740) protein (Fc Tag) Protein ABIN2693230 14 to 16 Days 50 μg $505.35 element-ABIN2693230
Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 2 (ACE2) (AA 18-740) protein (AVI tag,Biotin,His tag) Protein ABIN6952431 2 to 3 Days 200 μg $1,518.00 element-ABIN6952431
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 2 (ACE2) antibody Primary ABIN1169449 5 to 8 Days 100 μg $391.88 element-ABIN1169449
anti-Coronavirus (CoV) antibody Primary ABIN3027526 9 to 11 Days 1 mg $575.93 element-ABIN3027526
anti-MERS-Coronavirus (MERS-CoV) (N-Term) antibody Primary ABIN1995457 14 to 16 Days 100 μL $430.29 element-ABIN1995457
anti-MERS-Coronavirus Nucleocapsid Protein (MERS-CoV N) (AA 1-413) antibody Primary ABIN2000065 14 to 16 Days 100 μL $352.65 element-ABIN2000065
anti-MERS-Coronavirus Spike Protein (MERS-CoV S) (AA 1-725) antibody Primary ABIN5508501 14 to 16 Days 100 μL $473.32 element-ABIN5508501
anti-SARS-Coronavirus 3CL Protease antibody Primary ABIN129545 1 to 2 Days 500 μg $708.00 element-ABIN129545
anti-SARS-Coronavirus Membrane Protein (SARS-CoV M) (C-Term) antibody Primary ABIN233794 1 to 2 Days 100 μL $613.50 element-ABIN233794
anti-SARS-Coronavirus Nonstructural Protein 3 (SARS-CoV NSP3) antibody Primary ABIN233791 1 to 2 Days 100 μL $613.50 element-ABIN233791
anti-SARS-Coronavirus Nonstructural Protein 8 (SARS-CoV NSP8) antibody Primary ABIN233792 1 to 2 Days 100 μL $613.50 element-ABIN233792
anti-SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) antibody Primary ABIN129544 1 to 2 Days 500 μg $708.00 element-ABIN129544
anti-SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (C-Term) antibody Primary ABIN1030641 2 to 3 Days 0.1 mg $370.00 element-ABIN1030641
MERS-Coronavirus (MERS-CoV) (AA 1-725) (Active) protein (His tag) Protein ABIN2006896 14 to 16 Days 100 μg $699.47 element-ABIN2006896
MERS-Coronavirus (MERS-CoV) (AA 367-606), (Receptor Binding Domain) protein (His tag) Protein ABIN2006908 14 to 16 Days 100 μg $699.47 element-ABIN2006908

Need Help? Call our PhD Customer Support!

We help you with finding the right product for your research.

We currently offer more than 300 antibodies, kits, proteins, lysates for Coronavirus research.

Contact us via email or phone: (877) 302 8632 (US) or +49 241 95 163 153 (International)

Products for Coronavirus Proteins

CoV consists of four proteins with the being the most important surface protein. Find relevant products, antibodies, kits, proteins, assays:

  • Spike Protein:
  • Envelope Protein:
  • Membrane Protein:
  • Nucleocapsid Protein:

Structure of Coronavirus

nCoV Coronavirus structure - antibodies-online.com

SARS-CoV Spike Protein Antibodies

The coronavirus spike contains three segments: a large ectodomain, a single-pass transmembrane anchor, and a short intracellular tail. The ectodomain consists of a receptor-binding subunit S1 and a membrane-fusion subunit S2. During virus entry, S1 binds to a receptor on the host cell surface for viral attachment, and S2 fuses the host and viral membranes, allowing viral genomes to enter host cells.(7)

Below you will find a selection of our CoV spike protein antibodies. Click on the links to see more details.

Product Reactivity Clonality Application Cat. No. Quantity Relevance ProductGrid: uniqueid
anti-SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (C-Term) antibody Coronavirus (2019-nCoV), SARS Coronavirus (SARS-CoV) Polyclonal ELISA ABIN1030641 0.1 mg element-ABIN1030641
anti-SARS-Coronavirus Spike Protein (SARS-CoV S) antibody (FITC) SARS Coronavirus (SARS-CoV) Polyclonal IF (p) ABIN725442 100 μL element-ABIN725442
anti-SARS-Coronavirus Spike Protein (SARS-CoV S) antibody SARS Coronavirus (SARS-CoV) Monoclonal WB, IF, IC, ELISA ABIN2452119 50 μg element-ABIN2452119
anti-SARS-Coronavirus Spike Protein (SARS-CoV S) (N-Term) antibody SARS Coronavirus (SARS-CoV) Polyclonal ELISA ABIN1031553 0.1 mg element-ABIN1031553
anti-SARS-Coronavirus Spike Protein (SARS-CoV S) (Intermediate Domain 3) antibody SARS Coronavirus (SARS-CoV) Polyclonal ELISA ABIN1031207 0.1 mg element-ABIN1031207
anti-SARS-Coronavirus Spike Protein (SARS-CoV S) (AA 755-769) antibody SARS Coronavirus (SARS-CoV) Polyclonal WB ABIN200034 100 μg element-ABIN200034
anti-SARS-Coronavirus Spike Protein (SARS-CoV S) (AA 19-35) antibody SARS Coronavirus (SARS-CoV) Polyclonal ELISA, WB ABIN199980 100 μg element-ABIN199980

SARS-CoV Nucleocapsid Protein Antibodies

Of all the coronaviral structural proteins, the N protein is the most abundant throughout infection, both in mRNA and protein levels. Compared to the mRNA levels of other structural genes, the mRNA of the N protein is expressed three to ten times higher at 12-hour post-infection.(8)

Below you will find a selection of our CoV SARS-CoV Nucleocapsid protein antibodies. Take a look at SARS-CoV N antibody ABIN129544. The Immunogen has 90% homology with SARS-CoV-2 Nucleocapsid.

Product Reactivity Clonality Application Cat. No. Quantity Relevance ProductGrid: uniqueid
anti-SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) antibody Coronavirus (2019-nCoV) Monoclonal ABIN6952432 0.1 mg element-ABIN6952432
anti-SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) antibody Coronavirus (2019-nCoV) Polyclonal ABIN6952440 100 μL element-ABIN6952440
anti-SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) antibody Coronavirus (2019-nCoV) Monoclonal ABIN6952435 100 μL element-ABIN6952435
anti-SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) (AA 1-422) antibody SARS Coronavirus (SARS-CoV) Polyclonal ELISA ABIN2214569 100 μL element-ABIN2214569
anti-SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) antibody SARS Coronavirus (SARS-CoV) Polyclonal WB, ELISA ABIN129544 500 μg element-ABIN129544

SARS-CoV Envelope Protein Antibodies

The E protein is the smallest of the major structural proteins, but also the most enigmatic. During the replication cycle, E is abundantly expressed inside the infected cell, but only a small portion is incorporated into the virion envelope. The majority of the protein is localised at the site of intracellular trafficking.(9)

Below you will find a selection of our SARS-CoV Envelope protein antibodies. Click on the links to see more details.

Product Reactivity Clonality Application Cat. No. Quantity Relevance ProductGrid: uniqueid
anti-SARS-Coronavirus Envelope Protein (SARS-CoV E) (AA 59-70) antibody SARS Coronavirus (SARS-CoV) Polyclonal ELISA, WB ABIN199987 100 μg element-ABIN199987
anti-SARS-Coronavirus Envelope Protein (SARS-CoV E) (N-Term) antibody SARS Coronavirus (SARS-CoV) Polyclonal ELISA ABIN1003111 100 μg element-ABIN1003111
anti-SARS-Coronavirus Envelope Protein (SARS-CoV E) (C-Term) antibody SARS Coronavirus (SARS-CoV) Polyclonal ELISA ABIN1030639 0.1 mg element-ABIN1030639
anti-SARS-CoV-2 Envelope Protein (SARS-CoV-2 E) (N-Term) antibody Coronavirus (2019-nCoV), SARS Coronavirus (SARS-CoV) Polyclonal ELISA ABIN1031551 0.1 mg element-ABIN1031551

SARS-CoV Membrane Protein Antibodies

The coronavirus membrane (M) protein is the key player in virion assembly. One of its functions is to mediate the incorporation of the spikes into the viral envelope. When expressed alone, it accumulates in the Golgi complex in homomultimeric complexes. However, in combination with the E protein, virus-like particles (VLPs) similar to authentic virions in size and shape are assembled, demonstrating that the M and E proteins are the minimal requirements for envelope formation.(10)

Below you will find a selection of our SARS-CoV membrane protein antibodies. Click on the links to see more details.

Product Reactivity Clonality Application Cat. No. Quantity Relevance ProductGrid: uniqueid
anti-SARS-Coronavirus Membrane Protein (SARS-CoV M) antibody Human, Mouse (Murine) Monoclonal WB, ELISA ABIN966994 1 mL element-ABIN966994
anti-SARS-Coronavirus Membrane Protein (SARS-CoV M) (C-Term) antibody SARS Coronavirus (SARS-CoV) Polyclonal WB, IP, IEM, FM ABIN233794 100 μL element-ABIN233794
anti-SARS-Coronavirus Membrane Protein (SARS-CoV M) (Internal Region) antibody SARS Coronavirus (SARS-CoV) Polyclonal ELISA ABIN1003116 100 μg element-ABIN1003116

Products for NSPs - Potential Targets to Antiviral Agents

Similar to SARS and MERS, the SARS-CoV-2 genome encodes non-structural proteins (NSPs) (such as 3-chymotrypsin-like protease, papain-like protease, helicase, and RNA-dependent RNA polymerase), structural proteins (such as spike glycoprotein) and accessory proteins. The four non-structural proteins are key enzymes in the viral life cycle, and the spike glycoprotein is indispensable for virus–cell receptor interactions during viral entry. These five proteins were therefore recognized as attractive targets to develop antiviral agents against SARS and MERS.(6) We offer the following polyclonal antibodies for the NSP3, NSP5, NSP12, NSP13:

Best-selling antibody against SARS-CoV NSP3

The recombinant NSP3 antibody ABIN233791 is directed against SARS-Coronavirus nsp3 protein. The whole rabbit serum was produced by repeated immunizations with 3 E. coli derived proteins representing different parts of the SARS-CoV Nsp3 protein: aa 834-943 of polyprotein 1a (ADRP domain), aa 1208-1557 of polyprotein 1a (SARS-Unique Domain), aa 1558-2040 of polyprotein 1a (Papain-like proteinase domain). See more information and 6 PubMed references by clicking the link:

anti-SARS-Coronavirus Nonstructural Protein 3 (SARS-CoV NSP3) antibody
anti-SARS-Coronavirus Nonstructural Protein 8 (SARS-CoV NSP8) antibody

Products for nCoV Receptors

Current research indicates that is the key receptor that enables nCoV to enter the cells.(5) Antibodies and kits related to ACE2 and other receptors discussed in the literature are listed below.

Related Products

Coronavirus HCoV-EMC/2012 Proteome Microarray (ABIN6936258)

Coronavirus Expression Vectors and Cloning Vectors at genomics-online.com.

SARS-CoV-2 / 2019-nCoV: Vaccines, Therapeutics and Diagnostics to prevent and control Infections

antibodies-online.com: Making the Complex Convenient

300 Coronavirus-related antibodies, proteins, kits and lysates covering all relevant targets and viruses

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References

(1) WHO 01/12/2020, 02/11/2020 www.who.int/emergencies/diseases/novel-coronavirus-2019 , www.who.int/dg/speeches/detail/who-director-general-s-remarks-at-the-media-briefing-on-2019-ncov-on-11-february-2020

(2) Gorbalenya, Alexander E. "Severe acute respiratory syndrome-related coronavirus – The species and its viruses, a statement of the Coronavirus Study Group" 11 February 2020. doi:10.1101/2020.02.07.937862..

(3) Roujian Lu, Xiang Zhao, Juan Li, Peihua Niu, Bo Yang, Honglong Wu et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. January 30, 2020. www.thelancet.com/journals/.

(4) Wu,F., Zhao,S., Yu,B. A new coronavirus associated with human respiratory disease in China. January 05, 2020.PubMed32015508, Sequence

(5) Jia HP, Look DC, Shi L, Hickey M, Pewe L, Netland J, Farzan M, Wohlford-Lenane C, Perlman S, McCray PB Jr. ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia. J Virol. 2005 Dec;79(23):14614-21. doi: 10.1128/JVI.79.23.14614-14621.2005. PMID: 16282461; PMCID: PMC1287568.

(6) Therapeutic options for the 2019 novel coronavirus (2019-nCoV). Guangdi Li, Erik De Clercq. Nature Reviews Drug Discovery 19, 149-150 (2020). doi: 10.1038/d41573-020-00016-0

(7) Li F. Structure, Function, and Evolution of Coronavirus Spike Proteins. Annu Rev Virol. 2016 Sep 29;3(1):237-261. doi: 10.1146/annurev-virology-110615-042301. Epub 2016 Aug 25. PMID: 27578435; PMCID: PMC5457962.

(8) Li S, Lin L, Wang H, Yin J, Ren Y, Zhao Z, Wen J, Zhou C, Zhang X, Li X, Wang J, Zhou Z, Liu J, Shao J, Lei T, Fang J, Xu N, Liu S. The epitope study on the SARS-CoV nucleocapsid protein. Genomics Proteomics Bioinformatics. 2003 Aug;1(3):198-206. doi: 10.1016/s1672-0229(03)01025-8. PMID: 15629032; PMCID: PMC5172353.

(9) Schoeman D, Fielding BC. Coronavirus envelope protein: current knowledge. Virol J. 2019 May 27;16(1):69. doi: 10.1186/s12985-019-1182-0. PMID: 31133031; PMCID: PMC6537279.

(10) de Haan CA, Smeets M, Vernooij F, Vennema H, Rottier PJ. Mapping of the coronavirus membrane protein domains involved in interaction with the spike protein. J Virol. 1999 Sep;73(9):7441-52. PMID: 10438834; PMCID: PMC104271.