anti-Human FGF2 antibody for Functional Studies

Recommended FGF2 Antibody (supplied by: Log in to see )

Antigen
Fibroblast Growth Factor 2 (Basic) (FGF2) Antibodies
  • Fgf-2
  • Fgfb
  • bFGF
  • FGF-2
  • BFGF
  • FGFB
  • HBGF-2
  • fibroblast growth factor 2
  • fibroblast growth factor 2 (basic)
  • Fgf2
  • fgf2
  • FGF2
Reactivity
Human
330
74
60
38
25
20
4
3
2
2
2
2
1
1
Host
Rabbit
198
155
8
6
1
1
Clonality
Polyclonal
Conjugate
This FGF2 antibody is un-conjugated
34
19
13
9
8
5
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Western Blotting (WB)
273
223
102
66
33
28
27
17
15
14
13
13
11
7
6
4
4
2
2
1
1
1
1
1
1
1
1
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Catalog No. ABIN115676
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN115677 Func WB Rabbit Log in to see Polyclonal 0
1 ABIN116009 EIA Func IHC (p) WB Rabbit Log in to see Polyclonal 0
1 ABIN116010 EIA Func IHC (p) WB Rabbit Log in to see Polyclonal 0
1 ABIN2473613 Func IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal 1
1 ABIN187643 Func RIA Mouse IgG1 Log in to see BFM-1 2
1 ABIN640565 Func IHC (p) ELISA WB Rabbit Log in to see 0

General

Antigen Fibroblast Growth Factor 2 (Basic) (FGF2) Antibodies
Reactivity Human
(330), (74), (60), (38), (25), (20), (4), (3), (2), (2), (2), (2), (1), (1)
Host Rabbit
(198), (155), (8), (6), (1), (1)
Clonality
Polyclonal
Conjugate This FGF2 antibody is un-conjugated
(34), (19), (13), (9), (8), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Western Blotting (WB)
(273), (223), (102), (66), (33), (28), (27), (17), (15), (14), (13), (13), (11), (7), (6), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-FGF2 Antibody

Target Details FGF2 Application Details Handling Images
Specificity The antibody will detect FGF-2 (basic).
Purification Protein A affinity chromatography
Immunogen Highly pure (> 98%) recombinant human FGF-2 (basic)

Target Details FGF2

Product Details anti-FGF2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name FGF Basic / FGF2 (FGF2 Antibody Abstract)
Background FGF basic (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF2 mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.Synonyms: BFGF, FGFB, Fibroblast growth factor 2 (basic), HBGF-2, HBGF2, Heparin-binding growth factor 2
Gene ID 2247
NCBI Accession NP_001997
UniProt P09038
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus

Application Details

Product Details anti-FGF2 Antibody Target Details FGF2 Handling Images back to top
Application Notes Neutralization: To yield one-half maximal inhibition (ND50) of the biological activity of human FGF-2 basic(5 ng/mL) on HUVEC cells, a concentration of about 3.5 μg/mL of this antibody is required. Western Blot: To detect human FGF-2 basic by Western blot this antibody can be used at a concentrationof 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detectionlimit for recombinant human FGF-2 (basic) is 1.5 -3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-FGF2 Antibody Target Details FGF2 Application Details Images back to top
Reconstitution Restore in sterile water to a concentration of > / = 0.2 mg/mL.
Buffer PBS, pH 7.4, without stabilizer or preservative
Preservative Without preservative
Storage 4 °C/-20 °C
Storage Comment The lyophilized antibody is stable at room temperature for one month and for one year from despatch when kept at -20 °C. When reconstituted in sterile water to a concentration of > / = 0.2 mg/ml the antibody is stable for six weeks at 2-8 °C.
Expiry Date 12 months