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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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1 | ABIN1837323 | WB | Rabbit | C-Term | Log in to see | Polyclonal | 0 |
General |
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Antigen | Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) Antibodies |
Epitope | C-Term Alternatives |
Reactivity | Cow (Bovine), Dog (Canine), Goat, Guinea Pig, Horse (Equine), Human, Rabbit, Rat (Rattus) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This FLT1 antibody is un-conjugated Alternatives |
Application |
Western Blotting (WB)
Alternatives
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Supplier | Log in to see |
Product Details anti-FLT1 AntibodyTarget Details FLT1 Application Details Handling Images |
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Sequence | DLRVTSKSKE SGLSDVSRPS FCHSSCGHVS EGKRRFTYDH AELERKIACC |
Predicted Reactivity | Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 77%, Rat: 100% |
Characteristics | This is a rabbit polyclonal antibody against FLT1. It was validated on Western Blot. |
Purification | Affinity Purified |
Immunogen | The immunogen is a synthetic peptide directed towards the C-terminal region of Human FLT1 |
Plasmids, Primers & others | |
Target Details FLT1Product Details anti-FLT1 Antibody Application Details Handling Images back to top |
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Antigen | |
Alternative Name | FLT1 (FLT1 Antibody Abstract) |
Background |
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. Protein Interaction Partner: SRPK1, VEGFA, Nedd4, UBC, ATR, NRP2, NRP1, VEGFB, PTK2B, PGF, PTK2, SHC1, NCK1, PLCG2, KDR, PTPN11, PLCG1, FLT1, YES1, CRK, FYN, CTNNB1, GRB2, SHC2, PIK3R1, Protein Size: 463 |
Molecular Weight | 50 kDa |
Gene ID | 2321 |
Pathways | RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals |
Application DetailsProduct Details anti-FLT1 Antibody Target Details FLT1 Handling Images back to top |
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Restrictions | For Research Use only |
HandlingProduct Details anti-FLT1 Antibody Target Details FLT1 Application Details Images back to top |
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Format | Liquid |
Concentration | 1 mg/mL |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | Avoid repeat freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
ImagesProduct Details anti-FLT1 Antibody Target Details FLT1 Application Details Handling back to top |
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Supplier Images |