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|Antigen||Membrane Metallo-Endopeptidase (MME) Antibodies|
|Conjugate||This MME antibody is un-conjugated Alternatives|
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
|2 references available|
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Product Details anti-MME AntibodyTarget Details MME Application Details Handling References for anti-MME antibody (ABIN119107) Images
|Specificity||This antibody recognises the CD10 cell surface antigen.|
|Purification||Affinity chromatography on Protein G|
|Immunogen||Partially purified cell membrane antigens from fresh leukemia cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse PS/NS1/1-Ag4-1 myeloma cell line.|
Target Details MMEProduct Details anti-MME Antibody Application Details Handling References for anti-MME antibody (ABIN119107) Images back to top
|Alternative Name||CD10 / Neprilysin (MME Antibody Abstract)|
|Background||CD10 is a 100kD glycoprotein expressed by acute lymphoblastic leukaemia cells and by peripheral blood granulocytes. CD10 is also known as the Common Acute Lymphoblastic Leukaemia Antigen (CALLA).Synonyms: Atriopeptidase, CALLA, Common acute lymphocytic leukemia antigen, EPN, Enkephalinase, MME, NEP, Neutral endopeptidase, Neutral endopeptidase 24.11|
|Pathways||RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration|
Application DetailsProduct Details anti-MME Antibody Target Details MME Handling References for anti-MME antibody (ABIN119107) Images back to top
Flow cytometry. Immunoprecipitation. Immunohistochemistry on frozen sections. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-MME Antibody Target Details MME Application Details References for anti-MME antibody (ABIN119107) Images back to top
|Buffer||PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
References for anti-MME antibody (ABIN119107)Product Details anti-MME Antibody Target Details MME Application Details Handling Images back to top
Biddle, Haruta, Seon, Henderson, Sarcione: "In vitro and in vivo cytotoxic activity of anti-human leukemia monoclonal antibodies SN5c and SN6 daunorubicin conjugates." in: Leukemia research, Vol. 13, Issue 8, pp. 699-707, 1989
Matsuzaki, Haruta, Fukukawa, Barcos, Seon: "Unique epitopes of common acute lymphoblastic leukemia antigen detected by new monoclonal antibodies." in: Cancer research, Vol. 47, Issue 8, pp. 2160-6, 1987
ImagesProduct Details anti-MME Antibody Target Details MME Application Details Handling References for anti-MME antibody (ABIN119107) back to top