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|Antigen||Vascular Endothelial Growth Factor A (VEGFA) Antibodies|
|Epitope||AA 130-180 Alternatives|
|Reactivity||Guinea Pig, Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This VEGF antibody is un-conjugated Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|3 references available|
|Supplier||Log in to see|
Product Details anti-VEGF AntibodyTarget Details VEGF Application Details Handling References for anti-VEGF antibody (ABIN707186) Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human VEGF-A|
Target Details VEGFProduct Details anti-VEGF Antibody Application Details Handling References for anti-VEGF antibody (ABIN707186) Images back to top
|Alternative Name||VEGF-A (VEGFA Antibody Abstract)|
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.
Synonyms: VPF, VEGF, MVCD1, Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VEGFA
|Pathways||RTK Signaling, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling|
Application DetailsProduct Details anti-VEGF Antibody Target Details VEGF Handling References for anti-VEGF antibody (ABIN707186) Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-VEGF Antibody Target Details VEGF Application Details References for anti-VEGF antibody (ABIN707186) Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|
References for anti-VEGF antibody (ABIN707186)Product Details anti-VEGF Antibody Target Details VEGF Application Details Handling Images back to top
|Product cited in:||
Fetoni, Eramo, Paciello, Rolesi, Samengo, Paludetti, Troiani, Pani: "The redox protein p66(shc) mediates cochlear vascular dysfunction and transient noise-induced hearing loss." in: Scientific reports, Vol. 6, pp. 25450, 2016 Method employed by authors: Immunohistochemistry (Frozen Sections) (IHC (fro)) Further details: Sample: cochleae
Wang, Liao, Wang, Deng, Yu: "Transplantation of bone marrow stromal cells overexpressing human vascular endothelial growth factor 165 enhances tissue repair in a rat model of radiation-induced injury." in: Chinese medical journal, Vol. 127, Issue 6, pp. 1093-9, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).
Fetoni, Lattanzi, Eramo, Barba, Paciello, Moriconi, Rolesi, Michetti, Troiani, Paludetti: "Grafting and early expression of growth factors from adipose-derived stem cells transplanted into the cochlea, in a Guinea pig model of acoustic trauma." in: Frontiers in cellular neuroscience, Vol. 8, pp. 334, 2014 Method employed by authors: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Sample species: Pig (Porcine)).
ImagesProduct Details anti-VEGF Antibody Target Details VEGF Application Details Handling References for anti-VEGF antibody (ABIN707186) back to top