anti-Human VEGFR2 antibody for Enzyme Immunoassay

Recommended VEGFR2 Antibody (supplied by: Log in to see )

Antigen
Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
  • CD309
  • FLK1
  • VEGFR
  • VEGFR2
  • 6130401C07
  • Flk-1
  • Flk1
  • Krd-1
  • Ly73
  • VEGFR-2
  • sVEGFR-2
  • Vegfr-2
  • FLK-1
  • flk-1
  • vegfr-2
  • KDR
  • FLK/KDR
  • flk1
  • flk1b
  • kdrb
  • si:busm1-205d10.1
  • si:ch211-254j6.1
  • si:ch211-278f21.4
  • wu:fc31a09
  • kinase insert domain receptor
  • kinase insert domain protein receptor
  • vascular endothelial growth factor receptor kdr-like
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • KDR
  • Kdr
  • LOC100136647
  • kdr
Epitope
C-Term
79
61
56
40
28
24
24
22
21
21
19
16
15
15
14
12
12
10
10
9
8
7
7
7
7
7
6
6
6
5
5
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
760
415
213
28
14
8
5
5
5
4
3
2
2
2
2
2
2
2
1
1
1
1
1
Host
Rabbit
572
267
73
4
2
1
1
Clonality
Polyclonal
Conjugate
This VEGFR2 antibody is un-conjugated
52
40
33
32
23
22
20
13
13
13
12
11
9
9
8
8
8
8
6
6
5
5
5
5
4
3
3
3
3
3
3
2
2
2
2
2
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
581
329
328
299
234
152
145
59
41
31
26
18
17
8
8
8
7
6
5
2
1
1
1
1
Supplier
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Catalog No. ABIN359866
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN358131 EIA IHC (p) WB Rabbit Ig Fraction pTyr996 Log in to see Polyclonal 3
1 ABIN155179 EIA FACS IHC (fro) IF WB Mouse IgG1 Extracellular Domain Log in to see 4 (20I6) 1
1 ABIN115682 EIA Func IHC (fro) IP WB Rabbit Extracellular Domain Log in to see Polyclonal 3
1 ABIN155184 EIA Func IP WB Rabbit Extracellular Domain Log in to see Polyclonal 3
1 ABIN951293 EIA IHC (p) WB Rabbit Ig Fraction Log in to see Polyclonal 0
1 ABIN155185 EIA Func IHC (fro) IP WB Rabbit Extracellular Domain Log in to see Polyclonal 3
1 ABIN155183 EIA Func IP WB Biotin Rabbit Extracellular Domain Log in to see Polyclonal 3
1 ABIN155178 EIA FACS IHC (fro) IF WB Biotin Mouse IgG1 Extracellular Domain Log in to see 4 (20I6) 0
1 ABIN155176 EIA FACS WB Biotin Mouse IgG1 Extracellular Domain Log in to see 4H3 0
1 ABIN318152 EIA IHC (p) Rabbit pTyr1214 Log in to see Polyclonal 0
1 ABIN155161 EIA FACS IHC (fro) WB Biotin Mouse IgG1 Extracellular Domain Log in to see KDREIC 0
1 ABIN155177 EIA FACS WB Mouse IgG1 Extracellular Domain Log in to see 4H3 0
1 ABIN115148 EIA FACS IHC (fro) WB Mouse IgG1 Extracellular Domain Log in to see KDREIC 0
1 ABIN1106249 EIA FACS IF WB Mouse IgG1 Log in to see 4B4 3
1 ABIN115149 EIA FACS WB Mouse IgG1 Extracellular Domain Log in to see KDREWC 0
1 ABIN5541982 EIA FACS Rat IgG2a 3rd Extracellular Domain Log in to see BEP-5D8 0
1 ABIN5541983 EIA FACS Rat IgG2a 2nd Extracellular Domain Log in to see BEP-5A1 0
1 ABIN5541987 EIA FACS WB Biotin Mouse IgG1 Log in to see KDREWC 0

General

Antigen Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
Epitope C-Term
(79), (61), (56), (40), (28), (24), (24), (22), (21), (21), (19), (16), (15), (15), (14), (12), (12), (10), (10), (9), (8), (7), (7), (7), (7), (7), (6), (6), (6), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(760), (415), (213), (28), (14), (8), (5), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(572), (267), (73), (4), (2), (1), (1)
Clonality
Polyclonal
Conjugate This VEGFR2 antibody is un-conjugated
(52), (40), (33), (32), (23), (22), (20), (13), (13), (13), (12), (11), (9), (9), (8), (8), (8), (8), (6), (6), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(581), (329), (328), (299), (234), (152), (145), (59), (41), (31), (26), (18), (17), (8), (8), (8), (7), (6), (5), (2), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-VEGFR2 Antibody

Target Details VEGFR2 Application Details Handling References for anti-VEGFR2 antibody (ABIN359866) Images
Specificity This antibody reacts to VEGFR2.
Purification Affinity chromatography on Protein G
Immunogen KLH conjugated synthetic peptide selected from the C-terminal region of human KDR/FLK1
Isotype Ig Fraction
Plasmids, Primers & others

Target Details VEGFR2

Product Details anti-VEGFR2 Antibody Application Details Handling References for anti-VEGFR2 antibody (ABIN359866) Images back to top
Antigen
Alternative Name CD309 / VEGFR-2 / Flk-1 (KDR Antibody Abstract)
Background KDR (FLK1) is a receptor for VEGF or VEGFC. This protein has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.Synonyms: FLK1, KDR, Kinase NYK, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, VEGF Receptor 2, VEGFR2, Vascular endothelial growth factor receptor 2
Gene ID 3791, 9606
UniProt P35968
Pathways RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling

Application Details

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Handling References for anti-VEGFR2 antibody (ABIN359866) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details References for anti-VEGFR2 antibody (ABIN359866) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-VEGFR2 antibody (ABIN359866)

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling Images back to top
Background publications

Yilmaz, Kliche, Mayr-Beyrle, Fellbrich, Waltenberger: "p38 MAPK inhibition is critically involved in VEGFR-2-mediated endothelial cell survival." in: Biochemical and biophysical research communications, Vol. 306, Issue 3, pp. 730-6, 2003

Zeng, Zhao, Yang, Datta, Mukhopadhyay: "Heterotrimeric G alpha q/G alpha 11 proteins function upstream of vascular endothelial growth factor (VEGF) receptor-2 (KDR) phosphorylation in vascular permeability factor/VEGF signaling." in: The Journal of biological chemistry, Vol. 278, Issue 23, pp. 20738-45, 2003

Kiba, Yabana, Shibuya: "A set of loop-1 and -3 structures in the novel vascular endothelial growth factor (VEGF) family member, VEGF-ENZ-7, is essential for the activation of VEGFR-2 signaling." in: The Journal of biological chemistry, Vol. 278, Issue 15, pp. 13453-61, 2003

Elvert, Kappel, Heidenreich, Englmeier, Lanz, Acker, Rauter, Plate, Sieweke, Breier, Flamme: "Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha ) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1)." in: The Journal of biological chemistry, Vol. 278, Issue 9, pp. 7520-30, 2003

Yang, Toy, Ingle, Zlot, Williams, Fuh, Li, de Vos, Gerritsen: "Vascular endothelial growth factor-induced genes in human umbilical vein endothelial cells: relative roles of KDR and Flt-1 receptors." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 22, Issue 11, pp. 1797-803, 2002

Images

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling References for anti-VEGFR2 antibody (ABIN359866) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (C-Term) antibody (ABIN359866) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (C-Term) antibody (ABIN359866) Western blot analysis of anti-KDR/FLK1 Pab in HeLa cell lysate. KDR (VEGFR2) (arrow) ...