anti-Human VEGFR2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended VEGFR2 Antibody (supplied by: Log in to see )

Antigen
Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
  • vegfr-2
  • KDR
  • 6130401C07
  • Flk-1
  • Flk1
  • Krd-1
  • Ly73
  • VEGFR-2
  • VEGFR2
  • sVEGFR-2
  • Vegfr-2
  • CD309
  • FLK1
  • VEGFR
  • FLK-1
  • flk-1
  • FLK/KDR
  • flk1
  • flk1b
  • kdrb
  • si:busm1-205d10.1
  • si:ch211-254j6.1
  • si:ch211-278f21.4
  • wu:fc31a09
  • fk52c05
  • flk
  • kdr
  • kdra
  • vegfr2
  • vegfr4
  • vegr2
  • wu:fk52c05
  • vascular endothelial growth factor receptor kdr-like
  • kinase insert domain protein receptor
  • kinase insert domain receptor
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • kinase insert domain receptor like
  • LOC100136647
  • Kdr
  • KDR
  • kdr
  • kdrl
Epitope
C-Term
73
60
56
39
25
23
22
21
18
18
16
15
15
15
13
13
12
12
11
11
11
10
9
7
6
6
6
5
5
4
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
606
363
176
25
7
4
4
4
3
3
3
2
1
1
1
1
1
1
1
1
Host
Rabbit
527
144
60
4
2
1
1
Clonality
Polyclonal
Conjugate
This VEGFR2 antibody is un-conjugated
45
32
25
24
18
12
11
9
9
5
5
5
5
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
460
242
212
203
120
104
42
34
26
25
18
17
11
9
9
8
7
6
5
2
1
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN359866
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.623753 ABIN152109 IHC (fro) IHC (p) IHC Rabbit C-Term Log in to see Polyclonal 1
12.623753 ABIN2180045 FACS IHC (p) WB Rabbit IgG AA 150-190 Log in to see Polyclonal 4
12.623753 ABIN258820 IHC (p) IHC ELISA WB Mouse IgG1 N-Term Log in to see MM0002-2F66
12.623753 ABIN213630 IHC (p) Rabbit Internal Region Log in to see Polyclonal
12.623753 ABIN498218 IF IHC (p) Rabbit Log in to see Polyclonal
12.623753 ABIN2506667 ICC IF IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
12.623753 ABIN446800 ICC IF IHC (p) IHC Rabbit Log in to see Polyclonal
12.623753 ABIN951293 EIA IHC (p) WB Rabbit Ig Fraction Log in to see Polyclonal
12.623753 ABIN498809 IHC (p) WB Rabbit pTyr951 Log in to see Polyclonal
12.623753 ABIN498808 IHC (p) Rabbit pTyr1214 Log in to see Polyclonal
12.623753 ABIN498807 IHC (p) Rabbit pTyr1175 Log in to see Polyclonal
12.623753 ABIN498900 IHC (p) Rabbit Log in to see Polyclonal
12.623753 ABIN498899 IHC (p) Rabbit Log in to see Polyclonal
12.623753 ABIN498898 IHC (p) Rabbit Log in to see Polyclonal
12.623753 ABIN213631 IHC (p) Rabbit Internal Region Log in to see Polyclonal
1 ABIN358131 EIA IHC (p) WB Rabbit Ig Fraction pTyr996 Log in to see Polyclonal 3
1 ABIN389564 IHC (p) WB Rabbit Ig Fraction pTyr996 Log in to see Polyclonal 1
1 ABIN391979 FACS IF IHC (p) WB Rabbit Ig Fraction AA 1326-1356, C-Term Log in to see Polyclonal 4
1 ABIN152343 CyTOF ELISA FACS ICC IF IHC IHC (p) WB Mouse IgG1 Log in to see EIC 1
1 ABIN152058 IHC (p) IP IHC WB Rabbit C-Term, AA 1158-1365 Log in to see Polyclonal 8

General

Antigen Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
Epitope C-Term
(73), (60), (56), (39), (25), (23), (22), (21), (18), (18), (16), (15), (15), (15), (13), (13), (12), (12), (11), (11), (11), (10), (9), (7), (6), (6), (6), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(606), (363), (176), (25), (7), (4), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(527), (144), (60), (4), (2), (1), (1)
Clonality
Polyclonal
Conjugate This VEGFR2 antibody is un-conjugated
(45), (32), (25), (24), (18), (12), (11), (9), (9), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(460), (242), (212), (203), (120), (104), (42), (34), (26), (25), (18), (17), (11), (9), (9), (8), (7), (6), (5), (2), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
Supplier Log in to see

Product Details anti-VEGFR2 Antibody

Target Details VEGFR2 Application Details Handling References for anti-VEGFR2 antibody (ABIN359866) Images
Specificity This antibody reacts to VEGFR2.
Purification Affinity chromatography on Protein G
Immunogen KLH conjugated synthetic peptide selected from the C-terminal region of human KDR/FLK1
Isotype Ig Fraction

Target Details VEGFR2

Product Details anti-VEGFR2 Antibody Application Details Handling References for anti-VEGFR2 antibody (ABIN359866) Images back to top
Antigen
Alternative Name CD309 / VEGFR-2 / Flk-1 (KDR Antibody Abstract)
Background KDR (FLK1) is a receptor for VEGF or VEGFC. This protein has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.Synonyms: FLK1, KDR, Kinase NYK, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, VEGF Receptor 2, VEGFR2, Vascular endothelial growth factor receptor 2
Gene ID 3791, 9606
UniProt P35968
Research Area Cytokines, Receptors
Pathways RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling

Application Details

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Handling References for anti-VEGFR2 antibody (ABIN359866) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details References for anti-VEGFR2 antibody (ABIN359866) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-VEGFR2 antibody (ABIN359866)

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling Images back to top
Background publications

Yilmaz, Kliche, Mayr-Beyrle, Fellbrich, Waltenberger: "p38 MAPK inhibition is critically involved in VEGFR-2-mediated endothelial cell survival." in: Biochemical and biophysical research communications, Vol. 306, Issue 3, pp. 730-6, 2003

Zeng, Zhao, Yang, Datta, Mukhopadhyay: "Heterotrimeric G alpha q/G alpha 11 proteins function upstream of vascular endothelial growth factor (VEGF) receptor-2 (KDR) phosphorylation in vascular permeability factor/VEGF signaling." in: The Journal of biological chemistry, Vol. 278, Issue 23, pp. 20738-45, 2003

Kiba, Yabana, Shibuya: "A set of loop-1 and -3 structures in the novel vascular endothelial growth factor (VEGF) family member, VEGF-ENZ-7, is essential for the activation of VEGFR-2 signaling." in: The Journal of biological chemistry, Vol. 278, Issue 15, pp. 13453-61, 2003

Elvert, Kappel, Heidenreich, Englmeier, Lanz, Acker, Rauter, Plate, Sieweke, Breier, Flamme: "Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha ) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1)." in: The Journal of biological chemistry, Vol. 278, Issue 9, pp. 7520-30, 2003

Yang, Toy, Ingle, Zlot, Williams, Fuh, Li, de Vos, Gerritsen: "Vascular endothelial growth factor-induced genes in human umbilical vein endothelial cells: relative roles of KDR and Flt-1 receptors." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 22, Issue 11, pp. 1797-803, 2002

Images

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling References for anti-VEGFR2 antibody (ABIN359866) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (C-Term) antibody (ABIN359866) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (C-Term) antibody (ABIN359866) Western blot analysis of anti-KDR/FLK1 Pab in HeLa cell lysate. KDR (VEGFR2) (arrow) ...