anti-Human VEGFR2 antibody for Western Blotting

Recommended VEGFR2 Antibody (supplied by: Log in to see )

Antigen
Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
  • CD309
  • FLK1
  • VEGFR
  • VEGFR2
  • 6130401C07
  • Flk-1
  • Flk1
  • Krd-1
  • Ly73
  • VEGFR-2
  • sVEGFR-2
  • Vegfr-2
  • FLK-1
  • flk-1
  • vegfr-2
  • KDR
  • FLK/KDR
  • flk1
  • flk1b
  • kdrb
  • si:busm1-205d10.1
  • si:ch211-254j6.1
  • si:ch211-278f21.4
  • wu:fc31a09
  • kinase insert domain receptor
  • kinase insert domain protein receptor
  • vascular endothelial growth factor receptor kdr-like
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • KDR
  • Kdr
  • LOC100136647
  • kdr
Epitope
AA 20-764
80
61
56
40
28
24
24
22
21
20
19
16
15
15
14
12
12
10
10
9
8
7
7
7
7
6
6
6
6
5
5
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
760
414
213
28
14
8
5
5
5
4
3
2
2
2
2
2
2
2
1
1
1
1
1
Host
Mouse
573
266
72
4
2
1
1
Clonality
Monoclonal
Conjugate
This VEGFR2 antibody is un-conjugated
52
39
33
32
23
22
20
13
13
13
12
11
9
9
8
8
8
8
6
6
5
5
5
5
4
3
3
3
3
3
3
2
2
2
2
2
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), ELISA, Western Blotting (WB)
581
329
327
297
234
153
144
59
41
31
26
19
17
8
8
8
7
6
5
2
1
1
1
1
Options
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Catalog No. ABIN969231
$ 393.80
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
24.279976 ABIN6265973 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 5
22.779976 ABIN3044301 ICC IHC (fro) IHC (p) WB Rabbit IgG AA 454-469, Middle Region Log in to see Polyclonal 6
22.630095 ABIN3020301 IF IHC WB Rabbit pTyr1214 Log in to see Polyclonal 0
21.279976 ABIN5519021 CC IHC (p) WB Rabbit IgG AA 20-242 Log in to see Polyclonal 4
19.779976 ABIN2506667 ICC IF IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal 0
19.630095 ABIN3182009 ELISA IHC WB Rabbit IgG pTyr1175 Log in to see Polyclonal 0
19.630095 ABIN3182010 ELISA IF IHC WB Rabbit IgG pTyr1214 Log in to see Polyclonal 0
19.630095 ABIN3184635 ELISA IF IHC WB Rabbit IgG Ser7 Log in to see Polyclonal 0
19.630095 ABIN926995 IHC WB Rabbit N-Term Log in to see Polyclonal 0
18.85012 ABIN3020298 IF IHC WB Rabbit pTyr1175 Log in to see Polyclonal 0
17.35012 ABIN966448 FACS IF ELISA WB Mouse IgG1 Extracellular, AA 20-764 Log in to see 4B4 3
16.779976 ABIN6271210 ELISA ICC IF IHC WB Rabbit IgG pTyr996 Log in to see Polyclonal 0
16.779976 ABIN1078658 ICC IHC WB Rabbit IgG AA 46-320 Log in to see Polyclonal 0
16.779976 ABIN6256071 ELISA ICC IF IHC WB Rabbit IgG pTyr951 Log in to see Polyclonal 0
16.779976 ABIN2905486 IF/ICC IHC IP WB Rabbit AA 46-320 Log in to see Polyclonal 0
16.630095 ABIN3184634 ELISA IF IHC WB Rabbit IgG Ser696 Log in to see Polyclonal 0
16.630095 ABIN3184636 ELISA WB Rabbit IgG Ser70 Log in to see Polyclonal 0
16.630095 ABIN6254233 IF WB Goat IgG AA 20-125 Log in to see Polyclonal 0
16.630095 ABIN3020022 WB Rabbit pTyr1059 Log in to see Polyclonal 0
15.85012 ABIN2745582 FACS WB Mouse IgG1 Log in to see 3(4H3) 0

General

Antigen Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
Epitope AA 20-764
(80), (61), (56), (40), (28), (24), (24), (22), (21), (20), (19), (16), (15), (15), (14), (12), (12), (10), (10), (9), (8), (7), (7), (7), (7), (6), (6), (6), (6), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(760), (414), (213), (28), (14), (8), (5), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Host Mouse
(573), (266), (72), (4), (2), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This VEGFR2 antibody is un-conjugated
(52), (39), (33), (32), (23), (22), (20), (13), (13), (13), (12), (11), (9), (9), (8), (8), (8), (8), (6), (6), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), ELISA, Western Blotting (WB)
(581), (329), (327), (297), (234), (153), (144), (59), (41), (31), (26), (19), (17), (8), (8), (8), (7), (6), (5), (2), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-VEGFR2 Antibody

Target Details VEGFR2 Application Details Handling References for anti-VEGFR2 antibody (ABIN969231) Images
Purification Ascites
Immunogen Purified recombinant extracellular fragment of human KDR (aa20-764) fused with hIgGFc tag expressed in HEK293 cells.
Clone 4B4
Isotype IgG1
Plasmids, Primers & others

Target Details VEGFR2

Product Details anti-VEGFR2 Antibody Application Details Handling References for anti-VEGFR2 antibody (ABIN969231) Images back to top
Antigen
Alternative Name KDR (KDR Antibody Abstract)
Background KDR has also been designated as VEFR-2 (Vascular endothelial growth factor receptor 2), CD309 (cluster of differentiation 309) and Flk1 (fetal liver kinase 1). Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. KDR is one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
Molecular Weight 152 kDa
Gene ID 3791
HGNC 3791
Pathways RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling

Application Details

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Handling References for anti-VEGFR2 antibody (ABIN969231) Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only

Handling

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details References for anti-VEGFR2 antibody (ABIN969231) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

References for anti-VEGFR2 antibody (ABIN969231)

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling Images back to top
Background publications

Lee, Bone, Strege, Shanafelt, Jelinek, Kay: "VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia." in: Blood, Vol. 104, Issue 3, pp. 788-94, 2004

Product cited in:

Takahashi, Yamaguchi, Chida, Shibuya: "A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells." in: The EMBO journal, Vol. 20, Issue 11, pp. 2768-78, 2001

Images

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling References for anti-VEGFR2 antibody (ABIN969231) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (AA 20-764) antibody (ABIN969231) Figure 1: Flow cytometric analysis of HepG2 cells using KDR mouse mAb (green) and neg...
Immunocytochemistry (ICC) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (AA 20-764) antibody (ABIN969231) Figure 2: Confocal immunofluorescence analysis of Hela (left) and HepG2 (right) cells...
Western Blotting (WB) image for anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (AA 20-764) antibody (ABIN969231) Figure 3: Western blot analysis using KDR mouse mAb against extracellular domain of h...